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Modified Nucleosides, Nucleotides and Nucleic Acids via Click Azide-Alkyne Cycloaddition for Pharmacological Applications

The click azide = alkyne 1,3-dipolar cycloaddition (click chemistry) has become the approach of choice for bioconjugations in medicinal chemistry, providing facile reaction conditions amenable to both small and biological molecules. Many nucleoside analogs are known for their marked impact in cancer...

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Detalles Bibliográficos
Autores principales: Perrone, Daniela, Marchesi, Elena, Preti, Lorenzo, Navacchia, Maria Luisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196910/
https://www.ncbi.nlm.nih.gov/pubmed/34067312
http://dx.doi.org/10.3390/molecules26113100