Synthesis and Modeling of Ezetimibe Analogues

Ezetimibe is a well-known drug that lowers blood cholesterol levels by reducing its absorption in the small intestine when joining to Niemann-Pick C1-like protein (NPC1L1). A ligand-based study on ezetimibe analogues is reported, together with one-hit synthesis, highlighted in the study. A convenien...

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Detalles Bibliográficos
Autores principales: Salgado, Mateo M., Manchado, Alejandro, Nieto, Carlos T., Díez, David, Garrido, Narciso M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196997/
https://www.ncbi.nlm.nih.gov/pubmed/34067439
http://dx.doi.org/10.3390/molecules26113107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196997/
https://www.ncbi.nlm.nih.gov/pubmed/34067439
http://dx.doi.org/10.3390/molecules26113107

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