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Structure-Based Discovery of ABCG2 Inhibitors: A Homology Protein-Based Pharmacophore Modeling and Molecular Docking Approach

ABCG2 is an ABC membrane protein reverse transport pump, which removes toxic substances such as medicines out of cells. As a result, drug bioavailability is an unexpected change and negatively influences the ADMET (absorption, distribution, metabolism, excretion, and toxicity), leading to multi-drug...

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Detalles Bibliográficos
Autores principales:	Le, Minh-Tri, Hoang, Viet-Nham, Nguyen, Dac-Nhan, Bui, Thi-Hoang-Linh, Phan, Thien-Vy, Huynh, Phuong Nguyen-Hoai, Tran, Thanh-Dao, Thai, Khac-Minh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8197086/ https://www.ncbi.nlm.nih.gov/pubmed/34071039 http://dx.doi.org/10.3390/molecules26113115

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