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Inhibition of DNA Repair in Combination with Temozolomide or Dianhydrogalactiol Overcomes Temozolomide-Resistant Glioma Cells
SIMPLE SUMMARY: Glioblastoma is the most prevalent and lethal brain tumor. Temozolomide is usually used for the treatment of glioblastoma. The poor prognosis of the tumor is due to drug resistance and tumor heterogeneity. The mechanism of the resistance to temozolomide is various within the same tum...
Autores principales: | Ohba, Shigeo, Yamashiro, Kei, Hirose, Yuichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8197190/ https://www.ncbi.nlm.nih.gov/pubmed/34073837 http://dx.doi.org/10.3390/cancers13112570 |
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