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Enhanced Anti-Tumor Activity in Mice with Temozolomide-Resistant Human Glioblastoma Cell Line-Derived Xenograft Using SN-38-Incorporated Polymeric Microparticle

Glioblastoma multiforme (GBM) has remained one of the most lethal and challenging cancers to treat. Previous studies have shown encouraging results when irinotecan was used in combination with temozolomide (TMZ) for treating GBM. However, irinotecan has a narrow therapeutic index: a slight dose incr...

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Detalles Bibliográficos
Autores principales:	Yang, Tao-Chieh, Liu, Shih-Jung, Lo, Wei-Lun, Chen, Shu-Mei, Tang, Ya-Ling, Tseng, Yuan-Yun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8197307/ https://www.ncbi.nlm.nih.gov/pubmed/34074038 http://dx.doi.org/10.3390/ijms22115557

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