C-11, a New Antiepileptic Drug Candidate: Evaluation of the Physicochemical Properties and Impact on the Protective Action of Selected Antiepileptic Drugs in the Mouse Maximal Electroshock-Induced Seizure Model

C-11 is a hybrid compound derived from 2-(2,5-dioxopyrrolidin-1-yl) propanamide, with a wide spectrum of anticonvulsant activity and low neurotoxicity. The aim of this study was to determine the effects of C-11 on the protective action of various antiepileptic drugs (i.e., carbamazepine CBZ, lacosam...

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Detalles Bibliográficos
Autores principales: Zagaja, Mirosław, Szewczyk, Aleksandra, Szala-Rycaj, Joanna, Raszewski, Grzegorz, Chrościńska-Krawczyk, Magdalena, Abram, Michał, Kamiński, Krzysztof, Andres-Mach, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8197310/
https://www.ncbi.nlm.nih.gov/pubmed/34074008
http://dx.doi.org/10.3390/molecules26113144

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