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Ganoderic Acid A Promotes Amyloid-β Clearance (In Vitro) and Ameliorates Cognitive Deficiency in Alzheimer’s Disease (Mouse Model) through Autophagy Induced by Activating Axl

Alzheimer’s disease (AD) is thought to be caused by amyloid-β (Aβ) accumulation in the central nervous system due to deficient clearance. The aim of the present study was to investigate the effect of ganoderic acid A (GAA) on Aβ clearance in microglia and its anti-AD activity. Aβ degradation in BV2...

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Detalles Bibliográficos
Autores principales: Qi, Li-Feng-Rong, Liu, Shuai, Liu, Yu-Ci, Li, Ping, Xu, Xiaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8197357/
https://www.ncbi.nlm.nih.gov/pubmed/34074054
http://dx.doi.org/10.3390/ijms22115559