Repression of MUC1 Promotes Expansion and Suppressive Function of Myeloid-Derived Suppressor Cells in Pancreatic and Breast Cancer Murine Models

Myeloid-derived suppressor cells (MDSCs) are immature myeloid cells that are responsible for immunosuppression in tumor microenvironment. Here we report the impact of mucin 1 (MUC1), a transmembrane glycoprotein, on proliferation and functional activity of MDSCs. To determine the role of MUC1 in MDS...

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Detalles Bibliográficos
Autores principales: Sahraei, Mahnaz, Bose, Mukulika, Sanders, J. Alexa, De, Chandrav, DasRoy, Lopamudra, Nath, Sritama, Brouwer, Cory R., Mukherjee, Pinku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8197523/
https://www.ncbi.nlm.nih.gov/pubmed/34070449
http://dx.doi.org/10.3390/ijms22115587

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8197523/
https://www.ncbi.nlm.nih.gov/pubmed/34070449
http://dx.doi.org/10.3390/ijms22115587

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