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Etiological Factors of the Midline Diastema in Children: A Systematic Review

BACKGROUND: Midline diastema in children is a prevalent developmental entity, and this pathological condition may remain in many children due to various factors. Nonetheless, the evidence on etiological factors of the midline diastema in children is minimal. PURPOSE: To evaluate the etiological fact...

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Autores principales: Nuvvula, Sivakumar, Ega, Sravani, Mallineni, Sreekanth Kumar, Almulhim, Basim, Alassaf, Abdullah, Alghamdi, Sara Ayid, Chen, Yong, Aldhuwayhi, Sami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8197578/
https://www.ncbi.nlm.nih.gov/pubmed/34135623
http://dx.doi.org/10.2147/IJGM.S297462
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author Nuvvula, Sivakumar
Ega, Sravani
Mallineni, Sreekanth Kumar
Almulhim, Basim
Alassaf, Abdullah
Alghamdi, Sara Ayid
Chen, Yong
Aldhuwayhi, Sami
author_facet Nuvvula, Sivakumar
Ega, Sravani
Mallineni, Sreekanth Kumar
Almulhim, Basim
Alassaf, Abdullah
Alghamdi, Sara Ayid
Chen, Yong
Aldhuwayhi, Sami
author_sort Nuvvula, Sivakumar
collection PubMed
description BACKGROUND: Midline diastema in children is a prevalent developmental entity, and this pathological condition may remain in many children due to various factors. Nonetheless, the evidence on etiological factors of the midline diastema in children is minimal. PURPOSE: To evaluate the etiological factors of midline diastema causes in children below 12 years of age from the published data. METHODS: A literature search was confined to the English language using MeSH terms conferring to PICO format in PubMed, Cochrane Library, and Ovid(sp) covering the period from January 1960 to December 2019. Search in Google Scholar, grey literature, and hand search on references were performed to find additional data. Suitable studies were selected based on the predefined inclusion and exclusion criteria. Quality analysis of the chosen studies conducted using the Newcastle-Ottawa Scale (NOS) adapted for cross-sectional studies. RESULTS: Only eight studies were available for final analysis among those four studies from India, two studies from Korea, one study from Brazil, and another study from Canada. The most common etiology for midline diastema was supernumerary teeth followed by morphology labial frenum and nasal airflow condensation. The quality analysis of these studies based on NOS showed one study with unsatisfactory, four studies with satisfactory, and three with good quality. CONCLUSION: Morphology of frenum, pre-maxillary supernumerary teeth, and nasal airflow condensation seem to be the most common causes of midline diastema in children below 12 years.
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spelling pubmed-81975782021-06-15 Etiological Factors of the Midline Diastema in Children: A Systematic Review Nuvvula, Sivakumar Ega, Sravani Mallineni, Sreekanth Kumar Almulhim, Basim Alassaf, Abdullah Alghamdi, Sara Ayid Chen, Yong Aldhuwayhi, Sami Int J Gen Med Review BACKGROUND: Midline diastema in children is a prevalent developmental entity, and this pathological condition may remain in many children due to various factors. Nonetheless, the evidence on etiological factors of the midline diastema in children is minimal. PURPOSE: To evaluate the etiological factors of midline diastema causes in children below 12 years of age from the published data. METHODS: A literature search was confined to the English language using MeSH terms conferring to PICO format in PubMed, Cochrane Library, and Ovid(sp) covering the period from January 1960 to December 2019. Search in Google Scholar, grey literature, and hand search on references were performed to find additional data. Suitable studies were selected based on the predefined inclusion and exclusion criteria. Quality analysis of the chosen studies conducted using the Newcastle-Ottawa Scale (NOS) adapted for cross-sectional studies. RESULTS: Only eight studies were available for final analysis among those four studies from India, two studies from Korea, one study from Brazil, and another study from Canada. The most common etiology for midline diastema was supernumerary teeth followed by morphology labial frenum and nasal airflow condensation. The quality analysis of these studies based on NOS showed one study with unsatisfactory, four studies with satisfactory, and three with good quality. CONCLUSION: Morphology of frenum, pre-maxillary supernumerary teeth, and nasal airflow condensation seem to be the most common causes of midline diastema in children below 12 years. Dove 2021-06-08 /pmc/articles/PMC8197578/ /pubmed/34135623 http://dx.doi.org/10.2147/IJGM.S297462 Text en © 2021 Nuvvula et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Review
Nuvvula, Sivakumar
Ega, Sravani
Mallineni, Sreekanth Kumar
Almulhim, Basim
Alassaf, Abdullah
Alghamdi, Sara Ayid
Chen, Yong
Aldhuwayhi, Sami
Etiological Factors of the Midline Diastema in Children: A Systematic Review
title Etiological Factors of the Midline Diastema in Children: A Systematic Review
title_full Etiological Factors of the Midline Diastema in Children: A Systematic Review
title_fullStr Etiological Factors of the Midline Diastema in Children: A Systematic Review
title_full_unstemmed Etiological Factors of the Midline Diastema in Children: A Systematic Review
title_short Etiological Factors of the Midline Diastema in Children: A Systematic Review
title_sort etiological factors of the midline diastema in children: a systematic review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8197578/
https://www.ncbi.nlm.nih.gov/pubmed/34135623
http://dx.doi.org/10.2147/IJGM.S297462
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