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LINGO-1 shRNA protects the brain against ischemia/reperfusion injury by inhibiting the activation of NF-κB and JAK2/STAT3

LINGO-1 may be involved in the pathogenesis of cerebral ischemia. However, its biological function and underlying molecular mechanism in cerebral ischemia remain to be further defined. In our study, middle cerebral artery occlusion/reperfusion (MACO/R) mice model and HT22 cell oxygen–glucose depriva...

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Detalles Bibliográficos
Autores principales: Zhu, Jiaying, Zhu, Zhu, Ren, Yipin, Dong, Yukang, Li, Yaqi, Yang, Xiulin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8197719/
https://www.ncbi.nlm.nih.gov/pubmed/33830473
http://dx.doi.org/10.1007/s13577-021-00527-x