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Syndecan-1 Depletion Has a Differential Impact on Hyaluronic Acid Metabolism and Tumor Cell Behavior in Luminal and Triple-Negative Breast Cancer Cells

Glycosaminoglycans (GAGs) and proteoglycans (PGs) are major components of the glycocalyx. The secreted GAG and CD44 ligand hyaluronic acid (HA), and the cell surface PG syndecan-1 (Sdc-1) modulate the expression and activity of cytokines, chemokines, growth factors, and adhesion molecules, acting as...

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Detalles Bibliográficos
Autores principales: Valla, Sofía, Hassan, Nourhan, Vitale, Daiana Luján, Madanes, Daniela, Spinelli, Fiorella Mercedes, Teixeira, Felipe C. O. B., Greve, Burkhard, Espinoza-Sánchez, Nancy Adriana, Cristina, Carolina, Alaniz, Laura, Götte, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198019/
https://www.ncbi.nlm.nih.gov/pubmed/34070901
http://dx.doi.org/10.3390/ijms22115874