Incorporation of Sulfonamide Moiety into Biguanide Scaffold Results in Apoptosis Induction and Cell Cycle Arrest in MCF-7 Breast Cancer Cells

Metformin, apart from its glucose-lowering properties, has also been found to demonstrate anti-cancer properties. Anti-cancer efficacy of metformin depends on its uptake in cancer cells, which is mediated by plasma membrane monoamine transporters (PMAT) and organic cation transporters (OCTs). This s...

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Detalles Bibliográficos
Autores principales: Markowicz-Piasecka, Magdalena, Sadowski, Karol, Huttunen, Johanna, Sikora, Joanna, Huttunen, Kristiina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198066/
https://www.ncbi.nlm.nih.gov/pubmed/34073245
http://dx.doi.org/10.3390/ijms22115642

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198066/
https://www.ncbi.nlm.nih.gov/pubmed/34073245
http://dx.doi.org/10.3390/ijms22115642

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