Cargando…
Elevating the Levels of Calcium Ions Exacerbate Alzheimer’s Disease via Inducing the Production and Aggregation of β-Amyloid Protein and Phosphorylated Tau
Alzheimer’s disease (AD) is a neurodegenerative disease with a high incidence rate. The main pathological features of AD are β-amyloid plaques (APs), which are formed by β-amyloid protein (Aβ) deposition, and neurofibrillary tangles (NFTs), which are formed by the excessive phosphorylation of the ta...
Autores principales: | Guan, Pei-Pei, Cao, Long-Long, Wang, Pu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198078/ https://www.ncbi.nlm.nih.gov/pubmed/34072743 http://dx.doi.org/10.3390/ijms22115900 |
Ejemplares similares
-
Calcium Ions Stimulate the Hyperphosphorylation of Tau by Activating Microsomal Prostaglandin E Synthase 1
por: Cao, Long-Long, et al.
Publicado: (2019) -
Calcium Ions Aggravate Alzheimer’s Disease Through the Aberrant Activation of Neuronal Networks, Leading to Synaptic and Cognitive Deficits
por: Guan, Pei-Pei, et al.
Publicado: (2021) -
Tau aggregation and its interplay with amyloid-β
por: Nisbet, Rebecca M., et al.
Publicado: (2014) -
Amyloid-β-Derived Peptidomimetics Inhibits Tau
Aggregation
por: Gorantla, Nalini V., et al.
Publicado: (2021) -
Inhibitory Effects of Macelignan on Tau Phosphorylation and Aβ Aggregation in the Cell Model of Alzheimer's Disease
por: Gu, Liang, et al.
Publicado: (2022)