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Transcriptomic Profiling of the Liver Sinusoidal Endothelium during Cirrhosis Reveals Stage-Specific Secretory Signature
SIMPLE SUMMARY: We define the transcriptome and secretome of primary LSECs during the progression of cirrhosis, revealing specific molecular signatures, novel biomarkers and therapeutic targets for new disease-modifying treatments for patients with advanced chronic liver disease. ABSTRACT: The poor...
Autores principales: | Manicardi, Nicolò, Fernández-Iglesias, Anabel, Abad-Jordà, Laia, Royo, Felix, Azkargorta, Mikel, Ortega-Ribera, Martí, Sanfeliu-Redondo, David, Martínez-Alcocer, Ana, Elortza, Felix, Hessheimer, Amelia J., Fondevila, Constantino, Lozano, Juan José, García-Pagán, Juan Carlos, Bosch, Jaime, Cubero, Francisco Javier, Albillos, Agustín, Vaquero, Javier, Falcón-Pérez, Juan M., Gracia-Sancho, Jordi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198220/ https://www.ncbi.nlm.nih.gov/pubmed/34072510 http://dx.doi.org/10.3390/cancers13112688 |
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