The Amino Acid Transporter Mct10/Tat1 Is Important to Maintain the TSH Receptor at Its Canonical Basolateral Localization and Assures Regular Turnover of Thyroid Follicle Cells in Male Mice

Cathepsin K-mediated thyroglobulin proteolysis contributes to thyroid hormone (TH) liberation, while TH transporters like Mct8 and Mct10 ensure TH release from thyroid follicles into the blood circulation. Thus, thyroid stimulating hormone (TSH) released upon TH demand binds to TSH receptors of thyr...

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Detalles Bibliográficos
Autores principales: Venugopalan, Vaishnavi, Al-Hashimi, Alaa, Weber, Jonas, Rehders, Maren, Qatato, Maria, Wirth, Eva K., Schweizer, Ulrich, Heuer, Heike, Verrey, François, Brix, Klaudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198332/
https://www.ncbi.nlm.nih.gov/pubmed/34071318
http://dx.doi.org/10.3390/ijms22115776

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