Cargando…

IDO and CD40 May Be Key Molecules for Immunomodulatory Capacity of the Primed Tonsil-Derived Mesenchymal Stem Cells

Background: Tonsil-derived mesenchymal stem cells (T-MSCs) were reported to have suppressive effect on T cells, yet much remains unknown about the underlying mechanisms supporting this effect. We investigated the underlying mechanism of the immunomodulatory effect of T-MSCs on immune cell proliferat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Hyun-Joo, Jung, Harry, Kim, Dong-Kyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198434/ https://www.ncbi.nlm.nih.gov/pubmed/34071285 http://dx.doi.org/10.3390/ijms22115772

Ejemplares similares

TNF-α Priming Elicits Robust Immunomodulatory Potential of Human Tonsil-Derived Mesenchymal Stem Cells to Alleviate Murine Colitis
por: Shin, Tae-Hoon, et al.
Publicado: (2020)

Therapeutic Effect of IL1β Priming Tonsil Derived-Mesenchymal Stem Cells in Osteoporosis
por: Yoo, Minjoo, et al.
Publicado: (2021)

Occurrence of IL-1, IL-10, CD25, CD40, and CD69 in the tissue of palatine tonsils
por: Bant, Przemysław, et al.
Publicado: (2021)

Design, Synthesis, and Evaluation of Novel Immunomodulatory Small Molecules Targeting the CD40–CD154 Costimulatory Protein-Protein Interaction
por: Bojadzic, Damir, et al.
Publicado: (2018)

The Effect of Mesenchymal Stem Cells on the Expression of IDO and Qa2 Molecules in Dendritic Cells
por: Moravej, Ali, et al.
Publicado: (2019)

CD38: An Immunomodulatory Molecule in Inflammation and Autoimmunity
por: Piedra-Quintero, Zayda L., et al.
Publicado: (2020)

CD4 responses against IDO
por: Andersen, Mads Hald
Publicado: (2012)

Indoleamine 2,3-Dioxygenase (IDO) Downregulates the Cell Surface Expression of the CD4 Molecule
por: Huang, Guanyou, et al.
Publicado: (2012)

Platelets as Key Factors in Inflammation: Focus on CD40L/CD40
por: Cognasse, Fabrice, et al.
Publicado: (2022)

The immunomodulatory role of IDO1-Kynurenine-NAD(+) pathway in switching cold tumor microenvironment in PDAC
por: Anu, R. I., et al.
Publicado: (2023)

CD40L Priming of Platelets via NF‐κB Activation is CD40‐ and TAK1‐Dependent
por: Kojok, Kevin, et al.
Publicado: (2018)

Cd40-Independent Pathways of T Cell Help for Priming of Cd8(+) Cytotoxic T Lymphocytes
por: Lu, Zhengbin, et al.
Publicado: (2000)

Dexamethasone priming enhances stemness and immunomodulatory property of tissue-specific human mesenchymal stem cells
por: Rawat, Sonali, et al.
Publicado: (2021)

Analysis of Tonsil Tissues from Patients Diagnosed with Chronic Tonsillitis—Microbiological Profile, Biofilm-Forming Capacity and Histology
por: Kostić, Marina, et al.
Publicado: (2022)

Effect of Comedications and Endotoxins on Mesenchymal Stem Cell Secretomes, Migratory and Immunomodulatory Capacity
por: Durand, Nisha, et al.
Publicado: (2019)

Tumor endothelial cell up-regulation of IDO1 is an immunosuppressive feed-back mechanism that reduces the response to CD40-stimulating immunotherapy
por: Georganaki, Maria, et al.
Publicado: (2020)

Regenerative potential of tonsil mesenchymal stem cells on surgical cutaneous defect
por: Shin, Sung-Chan, et al.
Publicado: (2018)

CD105 (Endoglin)-Negative Murine Mesenchymal Stromal Cells Define a New Multipotent Subpopulation with Distinct Differentiation and Immunomodulatory Capacities
por: Anderson, Per, et al.
Publicado: (2013)

Application of Tonsil‐Derived Mesenchymal Stem Cells in Tissue Regeneration: Concise Review
por: Oh, Se‐Young, et al.
Publicado: (2019)

The Tonsils
Publicado: (1924)

Tonsilitis
Publicado: (1903)

Tonsilitis
Publicado: (1888)

Tonsillitis
por: De Blois, T. A.
Publicado: (1884)

Tonsilitis
por: Brooks, W. N.
Publicado: (1904)

Tonsilitis
por: Drueck, Charles J.
Publicado: (1910)

GABA is an effective immunomodulatory molecule
por: Jin, Zhe, et al.
Publicado: (2011)

Faecalibacterium prausnitzii Skews Human DC to Prime IL10-Producing T Cells Through TLR2/6/JNK Signaling and IL-10, IL-27, CD39, and IDO-1 Induction
por: Alameddine, Joudy, et al.
Publicado: (2019)

Blocking the CD40L-CD40 interaction in vivo specifically prevents the priming of T helper 1 cells through the inhibition of interleukin 12 secretion
Publicado: (1996)

Impact of IDO1 and IDO2 on the B Cell Immune Response
por: Merlo, Lauren M. F., et al.
Publicado: (2022)

Mesenchymal Stromal Cells Express GARP/LRRC32 on Their Surface: Effects on Their Biology and Immunomodulatory Capacity
por: Carrillo-Galvez, Ana Belén, et al.
Publicado: (2015)

Pre-conditioning of Equine Bone Marrow-Derived Mesenchymal Stromal Cells Increases Their Immunomodulatory Capacity
por: Caffi, Valeria, et al.
Publicado: (2020)

Immune combinational therapy targeting OX40 and IDO synergistically enhances efficacy of a cancer vaccine
por: Berrong, Zuzana, et al.
Publicado: (2014)

Human mesenchymal stromal cells enhance the immunomodulatory function of CD8(+)CD28(−) regulatory T cells
por: Liu, Qiuli, et al.
Publicado: (2015)

Immunomodulatory Factors in Primary Endometrial Cell Cultures Isolated from Cancer and Noncancerous Human Tissue–Focus on RAGE and IDO1
por: Tkaczuk-Włach, Joanna, et al.
Publicado: (2021)

Human Gingiva-Derived Mesenchymal Stem Cells Inhibit Xeno-Graft-versus-Host Disease via CD39–CD73–Adenosine and IDO Signals
por: Huang, Feng, et al.
Publicado: (2017)

Immunomodulatory plasticity of mesenchymal stem cells: a potential key to successful solid organ transplantation
por: Kaundal, Urvashi, et al.
Publicado: (2018)

Anatomy and physiology of the palatine tonsils, adenoids, and lingual tonsils
por: Arambula, Alexandra, et al.
Publicado: (2021)

The Supernatant of Tonsil-Derived Mesenchymal Stem Cell Has Antiallergic Effects in Allergic Rhinitis Mouse Model
por: Park, In-Su, et al.
Publicado: (2020)

IFN-Gamma and TNF-Alpha as a Priming Strategy to Enhance the Immunomodulatory Capacity of Secretomes from Menstrual Blood-Derived Stromal Cells
por: de Pedro, María Ángeles, et al.
Publicado: (2021)

Cd40 Ligand (Cd154) Triggers a Short-Term Cd4(+) T Cell Activation Response That Results in Secretion of Immunomodulatory Cytokines and Apoptosis
por: Blair, Patrick J., et al.
Publicado: (2000)

Cannot write session to /tmp/vufind_sessions/sess_he4k61fb8ffa8837kskh8l1j10