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O-GlcNAcylation Affects the Pathway Choice of DNA Double-Strand Break Repair

Exposing cells to DNA damaging agents, such as ionizing radiation (IR) or cytotoxic chemicals, can cause DNA double-strand breaks (DSBs), which are crucial to repair to maintain genetic integrity. O-linked β-N-acetylglucosaminylation (O-GlcNAcylation) is a post-translational modification (PTM), whic...

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Detalles Bibliográficos
Autores principales: Averbek, Sera, Jakob, Burkhard, Durante, Marco, Averbeck, Nicole B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198441/
https://www.ncbi.nlm.nih.gov/pubmed/34071949
http://dx.doi.org/10.3390/ijms22115715