Cargando…

Dual Mechanisms of Metabolism and Gene Expression of the CCRF-CEM Leukemia Cells under Glucocorticoid Treatment

Background: Glucocorticoids play an essential part in anti-leukemic therapies, but resistance is a crucial event for the prognosis of the disease. Glucocorticoids influence the metabolic properties of leukemic cells. The inherent plasticity of clinically evolving cancer cells justifies the character...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lambrou, George I., Karakonstantakis, Theodoros, Vlahopoulos, Spiros, Zaravinos, Apostolos
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198442/ https://www.ncbi.nlm.nih.gov/pubmed/34072627 http://dx.doi.org/10.3390/ijms22115889

Ejemplares similares

Cytotoxic Activity of Curcumin towards CCRF-CEM Leukemia Cells and Its Effect on DNA Damage
por: Kong, Yu, et al.
Publicado: (2009)

A Graphene Oxide-Based Fluorescent Aptasensor for the Turn-on Detection of CCRF-CEM
por: Tan, Jie, et al.
Publicado: (2018)

Regulatory Effect of Resveratrol and Prednisolone on MDR1 Protein Expression in Acute Lymphoblastic Leukemia Cell Line (CCRF-CEM)
por: Talebi, Mehdi, et al.
Publicado: (2019)

Correction to: A Graphene Oxide-Based Fluorescent Aptasensor for the Turn-on Detection of CCRF-CEM
por: Tan, Jie, et al.
Publicado: (2018)

Novel selection and genetic characterisation of an etoposide-resistant human leukaemic CCRF-CEM cell line.
por: Patel, S., et al.
Publicado: (1993)

Baicalein Triggers Mitochondria-Mediated Apoptosis and Enhances the Antileukemic Effect of Vincristine in Childhood Acute Lymphoblastic Leukemia CCRF-CEM Cells
por: Chen, Yun-Ju, et al.
Publicado: (2013)

Growth inhibition of human acute lymphoblastic CCRF-CEM leukemia cells by medicinal plants of the West-Canadian Gwich’in Native Americans
por: Deeg, Katharina, et al.
Publicado: (2012)

Genomic and transcriptomic profiling of resistant CEM/ADR-5000 and sensitive CCRF-CEM leukaemia cells for unravelling the full complexity of multi-factorial multidrug resistance
por: Kadioglu, Onat, et al.
Publicado: (2016)

17beta-estradiol promotes the synthesis and the secretion of annexin I in the CCRF-CEM human cell line.
por: Castro-Caldas, M, et al.
Publicado: (2001)

Comparison of Cytotoxic Activity of Bile on HepG2 and CCRF-CEM Cell Lines: An in Vitro Study
por: Azarpira, Negar, et al.
Publicado: (2012)

Reversal of vinblastine transport by chlorpromazine in membrane vesicles from multidrug-resistant human CCRF-CEM leukaemia cells.
por: Syed, S. K., et al.
Publicado: (1998)

Investigation of the Effect of Folic Acid Based Iron Oxide Nanoparticles on Human Leukemic CCRF-CEM Cell Line
por: Mehrabi, M, et al.
Publicado: (2013)

Synthesis of Tetrahydrohonokiol Derivates and Their Evaluation for Cytotoxic Activity against CCRF-CEM Leukemia, U251 Glioblastoma and HCT-116 Colon Cancer Cells
por: Bernaskova, Marketa, et al.
Publicado: (2014)

Apoptosis Induced by Prednisolone Occurs without Altering the Promoter Methylation of BAX and BCL-2 Genes in Acute Lymphoblastic Leukemia Cells CCRF-CEM
por: Ganbarjeddi, Saiedeh, et al.
Publicado: (2020)

Evaluation of BAX and BCL-2 Gene Expression and Apoptosis Induction in Acute Lymphoblastic Leukemia Cell Line CCRF-CEM after High- Dose Prednisolone Treatment
por: Ghasemi, Amin, et al.
Publicado: (2018)

Investigation of BAX and BCL2 expression and apoptosis in a resveratrol- and prednisolone-treated human T-ALL cell line, CCRF-CEM
por: Khanzadeh, Taghi, et al.
Publicado: (2018)

Acridone Derivative 8a Induces Oxidative Stress-Mediated Apoptosis in CCRF-CEM Leukemia Cells: Application of Metabolomics in Mechanistic Studies of Antitumor Agents
por: Wang, Yini, et al.
Publicado: (2013)

Identification of the Novel Interacting Partners of the Mammalian Target of Rapamycin Complex 1 in Human CCRF-CEM and HEK293 Cells
por: Rahman, Hazir, et al.
Publicado: (2014)

Implication of IRF4 Aberrant Gene Expression in the Acute Leukemias of Childhood
por: Adamaki, Maria, et al.
Publicado: (2013)

10058-F4, a c-Myc inhibitor, markedly increases valproic acid-induced cell death in Jurkat and CCRF-CEM T-lymphoblastic leukemia cells
por: MU, QITIAN, et al.
Publicado: (2014)

Real-time RT-PCR analysis of mRNA decay: half-life of Beta-actin mRNA in human leukemia CCRF-CEM and Nalm-6 cell lines
por: Leclerc, Guy J, et al.
Publicado: (2002)

Anticancer Drug‐mediated Induction of Multidrug Resistance‐associated Genes and Protein Kinase C Isozymes in the T‐Lymphoblastoid Cell Line CCRF‐CEM and in Blasts from Patients with Acute Lymphoblastic Leukemias
por: Beck, James F., et al.
Publicado: (2001)

Dexamethasone-induced and estradiol-induced CREB activation and annexin 1 expression in CCRF-CEM lymphoblastic cells: evidence for the involvement of cAMP and p38 MAPK.
por: Castro-Caldas, M, et al.
Publicado: (2003)

Elucidating the identity of resistance mechanisms to prednisolone exposure in acute lymphoblastic leukemia cells through transcriptomic analysis: A computational approach
por: Sifakis, Emmanouil G, et al.
Publicado: (2011)

Co-Deregulated miRNA Signatures in Childhood Central Nervous System Tumors: In Search for Common Tumor miRNA-Related Mechanics
por: Lambrou, George I., et al.
Publicado: (2021)

Fractal Dimensions of In Vitro Tumor Cell Proliferation
por: Lambrou, George I., et al.
Publicado: (2015)

Preclinical cellular pharmacology of LY231514 (MTA): a comparison with methotrexate, LY309887 and raltitrexed for their effects on intracellular folate and nucleoside triphosphate pools in CCRF-CEM cells.
por: Chen, V. J., et al.
Publicado: (1998)

Bryostatin-1, Fenretinide and 1α,25 (OH)(2)D(3) Induce Growth Inhibition, Apoptosis and Differentiation in T and B Cell-Derived Acute Lymphoblastic Leukemia Cell Lines (CCRF-CEM and Nalm-6)
por: Ardekani, Ali M., et al.
Publicado: (2011)

The Non-Coding RNA GAS5 and Its Role in Tumor Therapy-Induced Resistance
por: Lambrou, George I., et al.
Publicado: (2020)

Synchronisation by hydroxyurea does not affect the sensitivity of CEM-C7 lymphoblasts to glucocorticoids.
por: Maehira, F., et al.
Publicado: (1984)

Gravitational Influence on Human Living Systems and the Evolution of Species on Earth
por: Adamopoulos, Konstantinos, et al.
Publicado: (2021)

MYCN in Neuroblastoma: “Old Wine into New Wineskins”
por: Braoudaki, Maria, et al.
Publicado: (2021)

Poincaré Maps and Aperiodic Oscillations in Leukemic Cell Proliferation Reveal Chaotic Dynamics
por: Adamopoulos, Konstantinos, et al.
Publicado: (2021)

Progress in Treatment of Viral Infections in Children with Acute Lymphoblastic Leukemia
por: Moschovi, Maria, et al.
Publicado: (2016)

Spotlight on Differentially Expressed Genes in Urinary Bladder Cancer
por: Zaravinos, Apostolos, et al.
Publicado: (2011)

Identification of Common Differentially Expressed Genes in Urinary Bladder Cancer
por: Zaravinos, Apostolos, et al.
Publicado: (2011)

Editorial: Acute leukemias: molecular characterization, leukemia-initiating cells, and influence of the microenvironment
por: Dancik, Garrett M., et al.
Publicado: (2023)

Glucocorticoid evoked upregulation of RCAN1-1 in human leukemic CEM cells susceptible to apoptosis
por: Hirakawa, Yasuko, et al.
Publicado: (2009)

Glutamic Acid Increased Methotrexate Polyglutamation and Cytotoxicity in a CCRF-SB Acute Lymphoblastic Leukemia Cell Line
por: Mendoza-Santiago, Alma, et al.
Publicado: (2019)

Differential and Common Signatures of miRNA Expression and Methylation in Childhood Central Nervous System Malignancies: An Experimental and Computational Approach
por: Lambrou, George I., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_87n1c6jpk6s8gdj1ingbsephd9