Cargando…

The Odd Faces of Oligomers: The Case of TRAF2-C, A Trimeric C-Terminal Domain of TNF Receptor-Associated Factor

TNF Receptor Associated Factor 2 (TRAF2) is a trimeric protein that belongs to the TNF receptor associated factor family (TRAFs). The TRAF2 oligomeric state is crucial for receptor binding and for its interaction with other proteins involved in the TNFR signaling. The monomer-trimer equilibrium of a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Di Venere, Almerinda, Nicolai, Eleonora, Minicozzi, Velia, Caccuri, Anna Maria, Di Paola, Luisa, Mei, Giampiero
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198530/ https://www.ncbi.nlm.nih.gov/pubmed/34070875 http://dx.doi.org/10.3390/ijms22115871

Ejemplares similares

Polymorphism on human aromatase affects protein dynamics and substrate binding: spectroscopic evidence
por: Di Nardo, Giovanna, et al.
Publicado: (2021)

Dynamics and Flexibility of Human Aromatase Probed by FTIR and Time Resolved Fluorescence Spectroscopy
por: Di Nardo, Giovanna, et al.
Publicado: (2013)

The Puzzling Problem of Cardiolipin Membrane-Cytochrome c Interactions: A Combined Infrared and Fluorescence Study
por: Ripanti, Francesca, et al.
Publicado: (2021)

TRAF1/C5 locus is associated with response to anti-TNF in rheumatoid arthritis
por: Canhão, Helena, et al.
Publicado: (2012)

RP S19 C-terminal peptide trimer acts as a C5a receptor antagonist
por: Nishiura, Hiroshi, et al.
Publicado: (2016)

Replication of synthetic recognition-encoded oligomers by ligation of trimer building blocks
por: Núñez-Villanueva, Diego, et al.
Publicado: (2023)

The Diversity and Similarity of Transmembrane Trimerization of TNF Receptors
por: Zhao, Linlin, et al.
Publicado: (2020)

Conformational Heterogeneity and Cooperative Effects of Mammalian ALOX15
por: Ivanov, Igor, et al.
Publicado: (2021)

A novel PKD2L1 C-terminal domain critical for trimerization and channel function
por: Zheng, Wang, et al.
Publicado: (2015)

Epicatechin oligomers longer than trimers have anti-cancer activities, but not the catechin counterparts
por: Takanashi, Kohki, et al.
Publicado: (2017)

Therapeutic TNF Inhibitors can Differentially Stabilize Trimeric TNF by Inhibiting Monomer Exchange
por: van Schie, Karin A., et al.
Publicado: (2016)

The fine-tuning of TRAF2–GSTP1-1 interaction: effect of ligand binding and in situ detection of the complex
por: De Luca, A, et al.
Publicado: (2014)

The transmembrane domain and luminal C-terminal region independently support invariant chain trimerization and assembly with MHCII into nonamers
por: Cloutier, Maryse, et al.
Publicado: (2021)

X-ray Crystallographic Structure of Oligomers Formed by a Toxic β-Hairpin Derived from α-Synuclein: Trimers and Higher-Order Oligomers
por: Salveson, Patrick J., et al.
Publicado: (2016)

Changes in the C-terminal, N-terminal, and histidine regions of amelogenin reveal the role of oligomer quaternary structure on adsorption and hydroxyapatite mineralization
por: Tao, Jinhui, et al.
Publicado: (2022)

Bivalent IAP antagonists inhibit TRAF2-bound cIAPs and limit TNF-mediated NF-κB signaling
por: Condon, Stephen M
Publicado: (2016)

Small molecules that inhibit TNF signalling by stabilising an asymmetric form of the trimer
por: O’Connell, James, et al.
Publicado: (2019)

Thioether-Linked Liquid Crystal Trimers: Odd–Even Effects of Spacers and the Influence of Thioether Bonds on Phase Behavior
por: Arakawa, Yuki, et al.
Publicado: (2022)

Probing differences among Aβ oligomers with two triangular trimers derived from Aβ
por: Kreutzer, Adam G., et al.
Publicado: (2023)

TNF Receptor Associated Factor 2 (TRAF2) Signaling in Cancer
por: Siegmund, Daniela, et al.
Publicado: (2022)

Folding and fluorescence enhancement with strong odd–even effect for a series of merocyanine dye oligomers
por: Hu, Xiaobo, et al.
Publicado: (2021)

Expression of the odd-2 Gene in C. elegans
por: Charnysh, Elizabeth, et al.
Publicado: (2023)

c-Jun N-terminal kinase activation by nitrobenzoxadiazoles leads to late-stage autophagy inhibition
por: Palumbo, Camilla, et al.
Publicado: (2016)

Low-Expressing Synucleinopathy Mouse Models Based on Oligomer-Forming Mutations and C-Terminal Truncation of α-Synuclein
por: Martinez Hernandez, Ana, et al.
Publicado: (2021)

Regulation-Focused Psychotherapy for Children (RFP-C): Advances in the Treatment of ADHD and ODD in Childhood and Adolescence
por: Di Giuseppe, Mariagrazia, et al.
Publicado: (2020)

Strategic internal covalent cross-linking of TNF produces a stable TNF trimer with improved TNFR2 signaling
por: Ban, Liqin, et al.
Publicado: (2015)

TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1–TRAF2 complex to sensitize tumor cells to TNFα
por: Vince, James E., et al.
Publicado: (2008)

The role of TNF-receptor family members and other TRAF-dependent receptors in bone resorption
por: Gravallese, Ellen M, et al.
Publicado: (2001)

Induced Expression of Trimerized Intracellular Domains of the Human Tumor Necrosis Factor (TNF) p55 Receptor Elicits TNF Effects
por: Vandevoorde, Veronique, et al.
Publicado: (1997)

Figure-eight thermal hysteresis of aminomethylenehelicene oligomers with terminal C(16) alkyl groups during hetero-double-helix formation
por: Sawato, Tsukasa, et al.
Publicado: (2020)

M3 transition in odd and odd-odd nuclei
por: Roussière, B, et al.
Publicado: (1996)

Effects of microvirin monomers and oligomers on hepatitis C virus
por: Min, Yuan-Qin, et al.
Publicado: (2017)

TRAF2-MLK3 interaction is essential for TNF-α-induced MLK3 activation
por: Sondarva, Gautam, et al.
Publicado: (2009)

Crystal structure of TRIM20 C-terminal coiled-coil/B30.2 fragment: implications for the recognition of higher order oligomers
por: Weinert, Christopher, et al.
Publicado: (2015)

C-Cbl negatively regulates TRAF6-mediated NF-κB activation by promoting K48-linked polyubiquitination of TRAF6
por: Jang, Hyun-Duk, et al.
Publicado: (2019)

Polymorphisms in STAT4, PTPN2, PSORS1C1 and TRAF3IP2 Genes Are Associated with the Response to TNF Inhibitors in Patients with Rheumatoid Arthritis
por: Conigliaro, Paola, et al.
Publicado: (2017)

Activation of noncanonical NF-κB requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2, TRAF3 and the kinase NIK
por: Zarnegar, Brian J., et al.
Publicado: (2008)

Stabilization, Characterization, and Selective Removal of Cystatin C Amyloid Oligomers
por: Östner, Gustav, et al.
Publicado: (2013)

Structural Characterization of Covalently Stabilized Human Cystatin C Oligomers
por: Chrabąszczewska, Magdalena, et al.
Publicado: (2020)

Comparison of Target Recognition by TRAF1 and TRAF2
por: Kim, Chang Min, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_rrb1q95gctstmfqunpu09uo3kh