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IR-Surviving NSCLC Cells Exhibit Different Patterns of Molecular and Cellular Reactions Relating to the Multifraction Irradiation Regimen and p53-Family Proteins Expression

SIMPLE SUMMARY: For the first time, we demonstrated that the significant decrease in p63/p73 expression together with the absence of functional p53 could underlie an increase in the fraction of polyploid cells, transformation rates, and the glycolytic NAD(P)H production in multifraction X-ray radiat...

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Detalles Bibliográficos
Autores principales: Alhaddad, Lina, Pustovalova, Margarita, Blokhina, Taisia, Chuprov-Netochin, Roman, Osipov, Andreyan N., Leonov, Sergey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198560/
https://www.ncbi.nlm.nih.gov/pubmed/34071477
http://dx.doi.org/10.3390/cancers13112669