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Increased Expression of 11β-Hydroxysteroid Dehydrogenase Type 1 Contributes to Epidermal Permeability Barrier Dysfunction in Aged Skin

Inactive cortisone is converted into active cortisol by 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1). Excessive levels of active glucocorticoids could deteriorate skin barrier function; barrier impairment is also observed in aged skin. In this study, we aimed to determine whether permeability...

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Detalles Bibliográficos
Autores principales:	Kim, Beom Jun, Lee, Noo Ri, Lee, Chung Hyeok, Lee, Young Bin, Choe, Sung Jay, Lee, Solam, Hwang, Hyun Jee, Kim, Eunjung, Lavery, Gareth G., Shin, Kyong-Oh, Park, Kyungho, Choi, Eung Ho
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198579/ https://www.ncbi.nlm.nih.gov/pubmed/34072239 http://dx.doi.org/10.3390/ijms22115750

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