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Small Molecule Compounds Identified from Mixture-Based Library Inhibit Binding between Plasmodium falciparum Infected Erythrocytes and Endothelial Receptor ICAM-1
Specific adhesion of P. falciparum parasite-infected erythrocytes (IE) in deep vascular beds can result in severe complications, such as cerebral malaria, placental malaria, respiratory distress, and severe anemia. Cerebral malaria and severe malaria syndromes were associated previously with sequest...
Autores principales: | Chesnokov, Olga, Visitdesotrakul, Pimnitah, Kalani, Komal, Nefzi, Adel, Oleinikov, Andrew V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198633/ https://www.ncbi.nlm.nih.gov/pubmed/34073419 http://dx.doi.org/10.3390/ijms22115659 |
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