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Small Molecule Compounds Identified from Mixture-Based Library Inhibit Binding between Plasmodium falciparum Infected Erythrocytes and Endothelial Receptor ICAM-1

Specific adhesion of P. falciparum parasite-infected erythrocytes (IE) in deep vascular beds can result in severe complications, such as cerebral malaria, placental malaria, respiratory distress, and severe anemia. Cerebral malaria and severe malaria syndromes were associated previously with sequest...

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Detalles Bibliográficos
Autores principales: Chesnokov, Olga, Visitdesotrakul, Pimnitah, Kalani, Komal, Nefzi, Adel, Oleinikov, Andrew V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198633/
https://www.ncbi.nlm.nih.gov/pubmed/34073419
http://dx.doi.org/10.3390/ijms22115659

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