Smooth Muscle Specific Ablation of CXCL12 in Mice Downregulates CXCR7 Associated with Defective Coronary Arteries and Cardiac Hypertrophy

The chemokine CXCL12 plays a fundamental role in cardiovascular development, cell trafficking, and myocardial repair. Human genome-wide association studies even have identified novel loci downstream of the CXCL12 gene locus associated with coronary artery disease and myocardial infarction. Neverthel...

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Detalles Bibliográficos
Autores principales: Ghadge, Santhosh Kumar, Messner, Moritz, Seiringer, Herbert, Maurer, Thomas, Staggl, Simon, Zeller, Tanja, Müller, Christian, Börnigen, Daniela, Weninger, Wolfgang J., Geyer, Stefan H., Sopper, Sieghart, Krogsdam, Anne, Pölzl, Gerhard, Bauer, Axel, Zaruba, Marc-Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198701/
https://www.ncbi.nlm.nih.gov/pubmed/34072818
http://dx.doi.org/10.3390/ijms22115908

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