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Induction of the Proinflammatory Chemokine Interleukin-8 Is Regulated by Integrated Stress Response and AP-1 Family Proteins Activated during Coronavirus Infection

Infection induces the production of proinflammatory cytokines and chemokines such as interleukin-8 (IL-8) and IL-6. Although they facilitate local antiviral immunity, their excessive release leads to life-threatening cytokine release syndrome, exemplified by the severe cases of coronavirus disease 2...

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Detalles Bibliográficos
Autores principales: Zhu, Qing Chun, Li, Shumin, Yuan, Li Xia, Chen, Rui Ai, Liu, Ding Xiang, Fung, To Sing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198748/
https://www.ncbi.nlm.nih.gov/pubmed/34073283
http://dx.doi.org/10.3390/ijms22115646

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