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Circumventing Drug Treatment? Intrinsic Lethal Effects of Polyethyleneimine (PEI)-Functionalized Nanoparticles on Glioblastoma Cells Cultured in Stem Cell Conditions

SIMPLE SUMMARY: Glioblastoma (GB) is the most frequent brain cancer that is highly difficult to treat. As with many cancer types, associated cancer stem cells can act as a reservoir of cancer-initiating cells, constituting a major hurdle for successful therapy. Herein, we report on a discovery of th...

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Detalles Bibliográficos
Autores principales: Prabhakar, Neeraj, Merisaari, Joni, Le Joncour, Vadim, Peurla, Markus, Karaman, Didem Şen, Casals, Eudald, Laakkonen, Pirjo, Westermarck, Jukka, Rosenholm, Jessica M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198814/
https://www.ncbi.nlm.nih.gov/pubmed/34071918
http://dx.doi.org/10.3390/cancers13112631