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Evaluation of Oropharyngeal pH-Monitoring in the Assessment of Laryngopharyngeal Reflux

Background: Laryngopharyngeal reflux (LPR) is a prevalent disorder. The aim of the present retrospective cohort study was to evaluate oropharyngeal pH-monitoring using a novel scoring system for LPR. Methods: In a total of 180 consecutive patients with possible LPR, reflux symptom index (RSI), reflu...

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Autores principales: Horvath, Lukas, Hagmann, Patricia, Burri, Emanuel, Kraft, Marcel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198919/
https://www.ncbi.nlm.nih.gov/pubmed/34072412
http://dx.doi.org/10.3390/jcm10112409
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author Horvath, Lukas
Hagmann, Patricia
Burri, Emanuel
Kraft, Marcel
author_facet Horvath, Lukas
Hagmann, Patricia
Burri, Emanuel
Kraft, Marcel
author_sort Horvath, Lukas
collection PubMed
description Background: Laryngopharyngeal reflux (LPR) is a prevalent disorder. The aim of the present retrospective cohort study was to evaluate oropharyngeal pH-monitoring using a novel scoring system for LPR. Methods: In a total of 180 consecutive patients with possible LPR, reflux symptom index (RSI), reflux finding score (RFS), oropharyngeal pH-monitoring and transnasal esophagoscopy were carried out for further investigation. Results: In our series, 99 (55%) patients had severe LPR, 29 (16%) cases presented with moderate and 23 (13%) with mild severity, 9 (5%) subjects revealed neutral values, and 7 (4%) individuals were alkaline, while 13 (7%) patients had no LPR. In detecting LPR, the sensitivity, specificity and accuracy of oropharyngeal pH-monitoring was 95%, 93% and 94%, respectively. Conclusion: Oropharyngeal pH-monitoring is a reliable tool in the assessment of LPR, but the pH graphs have to be precisely analyzed and interpreted in context with other validated diagnostic tests.
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spelling pubmed-81989192021-06-14 Evaluation of Oropharyngeal pH-Monitoring in the Assessment of Laryngopharyngeal Reflux Horvath, Lukas Hagmann, Patricia Burri, Emanuel Kraft, Marcel J Clin Med Article Background: Laryngopharyngeal reflux (LPR) is a prevalent disorder. The aim of the present retrospective cohort study was to evaluate oropharyngeal pH-monitoring using a novel scoring system for LPR. Methods: In a total of 180 consecutive patients with possible LPR, reflux symptom index (RSI), reflux finding score (RFS), oropharyngeal pH-monitoring and transnasal esophagoscopy were carried out for further investigation. Results: In our series, 99 (55%) patients had severe LPR, 29 (16%) cases presented with moderate and 23 (13%) with mild severity, 9 (5%) subjects revealed neutral values, and 7 (4%) individuals were alkaline, while 13 (7%) patients had no LPR. In detecting LPR, the sensitivity, specificity and accuracy of oropharyngeal pH-monitoring was 95%, 93% and 94%, respectively. Conclusion: Oropharyngeal pH-monitoring is a reliable tool in the assessment of LPR, but the pH graphs have to be precisely analyzed and interpreted in context with other validated diagnostic tests. MDPI 2021-05-29 /pmc/articles/PMC8198919/ /pubmed/34072412 http://dx.doi.org/10.3390/jcm10112409 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Horvath, Lukas
Hagmann, Patricia
Burri, Emanuel
Kraft, Marcel
Evaluation of Oropharyngeal pH-Monitoring in the Assessment of Laryngopharyngeal Reflux
title Evaluation of Oropharyngeal pH-Monitoring in the Assessment of Laryngopharyngeal Reflux
title_full Evaluation of Oropharyngeal pH-Monitoring in the Assessment of Laryngopharyngeal Reflux
title_fullStr Evaluation of Oropharyngeal pH-Monitoring in the Assessment of Laryngopharyngeal Reflux
title_full_unstemmed Evaluation of Oropharyngeal pH-Monitoring in the Assessment of Laryngopharyngeal Reflux
title_short Evaluation of Oropharyngeal pH-Monitoring in the Assessment of Laryngopharyngeal Reflux
title_sort evaluation of oropharyngeal ph-monitoring in the assessment of laryngopharyngeal reflux
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198919/
https://www.ncbi.nlm.nih.gov/pubmed/34072412
http://dx.doi.org/10.3390/jcm10112409
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