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Development of a Rapid-Onset, Acid-Labile Linkage Polyplex-Mixed Micellar System for Anticancer Therapy

In the treatment of cancers, small interfering ribonucleic acids (siRNAs) are delivered into cells to inhibit the oncogenic protein’s expression; however, polyanions, hydrophilicity, and rapid degradations in blood, endosomal or secondary lysosomal degradation hamper clinal applications. In this stu...

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Detalles Bibliográficos
Autores principales:	Hung, Shiou-Fen, Wen, Yu-Han, Yu, Lu-Yi, Chiu, Hsin-Cheng, Chiang, Yi-Ting, Lo, Chun-Liang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198952/ https://www.ncbi.nlm.nih.gov/pubmed/34072925 http://dx.doi.org/10.3390/polym13111823

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