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Molecular Dynamics of Cobalt Protoporphyrin Antagonism of the Cancer Suppressor REV-ERBβ

Nuclear receptor REV-ERBβ is an overexpressed oncoprotein that has been used as a target for cancer treatment. The metal-complex nature of its ligand, iron protoporphyrin IX (Heme), enables the REV-ERBβ to be used for multiple therapeutic modalities as a photonuclease, a photosensitizer, or a fluore...

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Detalles Bibliográficos
Autores principales: Fakih, Taufik Muhammad, Kurniawan, Fransiska, Yusuf, Muhammad, Mudasir, Mudasir, Tjahjono, Daryono Hadi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198987/
https://www.ncbi.nlm.nih.gov/pubmed/34071361
http://dx.doi.org/10.3390/molecules26113251