Human Polymerase δ-Interacting Protein 2 (PolDIP2) Inhibits the Formation of Human Tau Oligomers and Fibrils

A central characteristic of Alzheimer’s disease (AD) and other tauopathies is the accumulation of aggregated and misfolded Tau deposits in the brain. Tau-targeting therapies for AD have been unsuccessful in patients to date. Here we show that human polymerase δ-interacting protein 2 (PolDIP2) intera...

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Detalles Bibliográficos
Autores principales: Kasho, Kazutoshi, Krasauskas, Lukas, Smirnovas, Vytautas, Stojkovič, Gorazd, Morozova-Roche, Ludmilla A., Wanrooij, Sjoerd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199196/
https://www.ncbi.nlm.nih.gov/pubmed/34071254
http://dx.doi.org/10.3390/ijms22115768

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199196/
https://www.ncbi.nlm.nih.gov/pubmed/34071254
http://dx.doi.org/10.3390/ijms22115768

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