Cargando…

A Novel off-the-Shelf Trastuzumab-Armed NK Cell Therapy (ACE1702) Using Antibody-Cell-Conjugation Technology

SIMPLE SUMMARY: Chimeric antigen receptor T cell therapy has shown its potency against hematologic malignancies in autologous settings but also limited success against solid tumors with severe adverse events, including fatal cases of cytokine releasing syndrome. The aim of this research is to develo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Hao-Kang, Hsiao, Ching-Wen, Yang, Sen-Han, Yang, Hsiu-Ping, Wu, Tai-Sheng, Lee, Chia-Yun, Lin, Yan-Liang, Pan, Janet, Cheng, Zih-Fei, Lai, Yan-Da, Hsiao, Shih-Chia, Tang, Sai-Wen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199224/ https://www.ncbi.nlm.nih.gov/pubmed/34072864 http://dx.doi.org/10.3390/cancers13112724

Ejemplares similares

Current Perspectives on “Off-The-Shelf” Allogeneic NK and CAR-NK Cell Therapies
por: Heipertz, Erica L., et al.
Publicado: (2021)

A novel endogenous CD16-Expressing Natural Killer Cell for cancer immunotherapy
por: Cheng, Zih-Fei, et al.
Publicado: (2021)

A Novel Allogeneic Rituximab-Conjugated Gamma Delta T Cell Therapy for the Treatment of Relapsed/Refractory B-Cell Lymphoma
por: Li, Hao-Kang, et al.
Publicado: (2023)

Current Perspectives on the Use of off the Shelf CAR-T/NK Cells for the Treatment of Cancer
por: Cutmore, Lauren C., et al.
Publicado: (2021)

1702 A Comparative Analysis of Tuberculous and Brucellar Spondylodiscitis
por: Koubaa, Makram, et al.
Publicado: (2014)

Anti-PSMA CAR-Engineered NK-92 Cells: An Off-the-Shelf Cell Therapy for Prostate Cancer
por: Montagner, Isabella Monia, et al.
Publicado: (2020)

Use of Cell and Genome Modification Technologies to Generate Improved “Off-the-Shelf” CAR T and CAR NK Cells
por: Morgan, Michael A., et al.
Publicado: (2020)

CAR‐NK cells from engineered pluripotent stem cells: Off‐the‐shelf therapeutics for all patients
por: Lu, Shi‐Jiang, et al.
Publicado: (2021)

P522: OFF-THE-SHELF CD33 CAR-NK CELL THERAPY FOR RELAPSE/REFRACTORY AML: FIRST-IN-HUMAN, PHASE I TRIAL
por: Huang, Ruihao, et al.
Publicado: (2023)

Towards Rehabilitation Robotics: Off-the-Shelf BCI Control of Anthropomorphic Robotic Arms
por: Athanasiou, Alkinoos, et al.
Publicado: (2017)

“UniCAR”-modified off-the-shelf NK-92 cells for targeting of GD2-expressing tumour cells
por: Mitwasi, Nicola, et al.
Publicado: (2020)

Drug Conjugated and Bispecific Antibodies for Multiple Myeloma: Improving Immunotherapies off the Shelf
por: Barilà, Gregorio, et al.
Publicado: (2021)

Development of Stem Cell-Derived Immune Cells for Off-the-Shelf Cancer Immunotherapies
por: Li, Yan-Ruide, et al.
Publicado: (2021)

Efficacy, safety and dose selection of AZD3759 in patients with untreated EGFR-mutated non-small-cell lung cancer and central nervous system metastases in China (CTONG1702-Arm 8): a multi-center, single-arm, phase 2 trial
por: Maggie Liu, Si-Yang, et al.
Publicado: (2023)

HLA Class I Knockout Converts Allogeneic Primary NK Cells Into Suitable Effectors for “Off-the-Shelf” Immunotherapy
por: Hoerster, Keven, et al.
Publicado: (2021)

Preclinical Evaluation of CRISPR-Edited CAR-NK-92 Cells for Off-the-Shelf Treatment of AML and B-ALL
por: Ureña-Bailén, Guillermo, et al.
Publicado: (2022)

Carcinogens off the Shelf?
por: Stewart, Bernard W
Publicado: (2018)

1702. Disseminated Candidiasis after Candidemia: Epidemiology, Diagnostic Evaluation, and Risk Factors
por: Whitehurst, Daniel, et al.
Publicado: (2023)

Spanish and French rivalry in the Gulf region of the United States, 1678-1702 : the beginnings of Texas and Pensacola
por: Dunn, William E. (William Edward), 1888-1966
Publicado: (1917)

Safe and effective off-the-shelf immunotherapy based on CAR.CD123-NK cells for the treatment of acute myeloid leukaemia
por: Caruso, Simona, et al.
Publicado: (2022)

Two for one: targeting BCMA and CD19 in B-cell malignancies with off-the-shelf dual-CAR NK-92 cells
por: Roex, Gils, et al.
Publicado: (2022)

Off the Shelf Fouling Management
por: Rittschof, Daniel
Publicado: (2017)

Straightforward Generation of Ultrapure Off-the-Shelf Allogeneic CAR-T Cells
por: Juillerat, Alexandre, et al.
Publicado: (2020)

Beyond αβ T cells: NK, iNKT, and γδT cell biology in leukemic patients and potential for off-the-shelf adoptive cell therapies for AML
por: Kent, Andrew, et al.
Publicado: (2023)

Gobierno militar y político del reino imperial de la Nueva España (1702)
por: Seijas y Lobera Francisco de
Publicado: (1986)

Protective effects of HY1702 on lipopolysaccharide-induced mild acute respiratory distress syndrome in mice
por: Wang, Mengfei, et al.
Publicado: (2020)

Adapter chimeric antigen receptor (AdCAR)-engineered NK-92 cells: an off-the-shelf cellular therapeutic for universal tumor targeting
por: Grote, Stefan, et al.
Publicado: (2020)

1702. Platelet Counts in Contezolid Complicated Skin and Soft Tissue Infection Phase 2 and Phase 3 Clinical Trials
por: Fang, Edward, et al.
Publicado: (2022)

1702. Assessing the Safety and Efficacy of Valganciclovir Dosing for Cytomegalovirus Prophylaxis in Solid Organ Transplant Recipients on Hemodialysis
por: Yee, Jason, et al.
Publicado: (2020)

OA17.02 COVID-19 Pandemic and Mental Health Status of Lung Cancer Patients in Indonesia
por: Afladhia, H., et al.
Publicado: (2021)

Chimeric Antigen Receptor-Engineered NK-92 Cells: An Off-the-Shelf Cellular Therapeutic for Targeted Elimination of Cancer Cells and Induction of Protective Antitumor Immunity
por: Zhang, Congcong, et al.
Publicado: (2017)

Development of a Lyophilized Off-the-Shelf Mesenchymal Stem Cell-Derived Acellular Therapeutic
por: Driscoll, Julia, et al.
Publicado: (2022)

CERN: Fast trigger logic off the shelf
Publicado: (1981)

Calibration of Off-the-Shelf Anisotropic Magnetoresistance Magnetometers
por: Schulz, Leonard, et al.
Publicado: (2019)

Off-the-shelf proximity biotinylation for interaction proteomics
por: Santos-Barriopedro, Irene, et al.
Publicado: (2021)

Creating Neo-nipples with “Off the Shelf” Parts
por: Bender, Ryan, et al.
Publicado: (2021)

Toward the development of true “off‐the‐shelf” synthetic T‐cell immunotherapy
por: Iriguchi, Shoichi, et al.
Publicado: (2019)

Development of allogeneic HSC-engineered iNKT cells for off-the-shelf cancer immunotherapy
por: Li, Yan-Ruide, et al.
Publicado: (2021)

Cavitation-induced traumatic cerebral contusion and intracerebral hemorrhage in the rat brain by using an off-the-shelf clinical shockwave device
por: Huang, Abel Po-Hao, et al.
Publicado: (2019)

Calreticulin arms NK cells against leukemia
por: Fucikova, Jitka, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_r29p0if73teoljg7b25frb4nhi