CDH1 Gene Mutation Hereditary Diffuse Gastric Cancer Outcomes: Analysis of a Large Cohort, Systematic Review of Endoscopic Surveillance, and Secondary Cancer Risk Postulation

SIMPLE SUMMARY: Some patients carry a mutated copy of the CDH1 gene that can lead to a very rare form of hereditary gastric cancer called signet-ring cell adenocarcinoma (SRCC). SRCCs rarely form visible tumors prior to spreading. Hence, patients are recommended to have prophylactic gastrectomies at...

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Detalles Bibliográficos
Autores principales: Benesch, Matthew G. K., Bursey, Stuart R., O’Connell, Andrew C., Ryan, Morag G., Howard, Carrie L., Stockley, Cecily C., Mathieson, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199234/
https://www.ncbi.nlm.nih.gov/pubmed/34073553
http://dx.doi.org/10.3390/cancers13112622

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