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5-HT(1A) Serotonergic, α-Adrenergic and Opioidergic Receptors Mediate the Analgesic Efficacy of Vortioxetine in Mice
Vortioxetine is a multimodal antidepressant drug that affects several brain neurochemicals and has the potential to induce various pharmacological effects on the central nervous system. Therefore, we investigated the centrally mediated analgesic efficacy of this drug and the mechanisms underlying th...
Autores principales: | Turan Yücel, Nazlı, Kandemir, Ümmühan, Demir Özkay, Ümide, Can, Özgür Devrim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199248/ https://www.ncbi.nlm.nih.gov/pubmed/34071269 http://dx.doi.org/10.3390/molecules26113242 |
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