Cargando…

Differential Effects of Fkbp4 and Fkbp5 on Regulation of the Proopiomelanocortin Gene in Murine AtT-20 Corticotroph Cells

The hypothalamic-pituitary-adrenal axis is stimulated in response to stress. When activated, it is suppressed by the negative feedback effect of glucocorticoids. Glucocorticoids directly inhibit proopiomelanocortin (Pomc) gene expression in the pituitary. Glucocorticoid signaling is mediated via glu...

Descripción completa

Detalles Bibliográficos
Autores principales: Kageyama, Kazunori, Iwasaki, Yasumasa, Watanuki, Yutaka, Niioka, Kanako, Daimon, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199270/
https://www.ncbi.nlm.nih.gov/pubmed/34072036
http://dx.doi.org/10.3390/ijms22115724