New Disulfiram Derivatives as MAGL-Selective Inhibitors

Monoacylglycerol lipase (MAGL) is a key enzyme in the human endocannabinoid system. It is also the main enzyme responsible for the conversion of 2-arachidonoyl glycerol (2-AG) to arachidonic acid (AA), a precursor of prostaglandin synthesis. The inhibition of MAGL activity would be beneficial for th...

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Detalles Bibliográficos
Autor principal: Omran, Ziad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199291/
https://www.ncbi.nlm.nih.gov/pubmed/34070869
http://dx.doi.org/10.3390/molecules26113296

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199291/
https://www.ncbi.nlm.nih.gov/pubmed/34070869
http://dx.doi.org/10.3390/molecules26113296

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