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Kcnj16 (Kir5.1) Gene Ablation Causes Subfertility and Increases the Prevalence of Morphologically Abnormal Spermatozoa
The ability of spermatozoa to swim towards an oocyte and fertilize it depends on precise K(+) permeability changes. Kir5.1 is an inwardly-rectifying potassium (Kir) channel with high sensitivity to intracellular H(+) (pHi) and extracellular K(+) concentration [K(+)](o), and hence provides a link bet...
Autores principales: | Poli, Giulia, Hasan, Sonia, Belia, Silvia, Cenciarini, Marta, Tucker, Stephen J., Imbrici, Paola, Shehab, Safa, Pessia, Mauro, Brancorsini, Stefano, D’Adamo, Maria Cristina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199489/ https://www.ncbi.nlm.nih.gov/pubmed/34205849 http://dx.doi.org/10.3390/ijms22115972 |
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