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Mechanisms of TDP-43 Proteinopathy Onset and Propagation
TDP-43 is an RNA-binding protein that has been robustly linked to the pathogenesis of a number of neurodegenerative disorders, including amyotrophic lateral sclerosis and frontotemporal dementia. While mutations in the TARDBP gene that codes for the protein have been identified as causing disease in...
Autores principales: | Chen, Han-Jou, Mitchell, Jacqueline C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199531/ https://www.ncbi.nlm.nih.gov/pubmed/34199367 http://dx.doi.org/10.3390/ijms22116004 |
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