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Mechanisms of TDP-43 Proteinopathy Onset and Propagation

TDP-43 is an RNA-binding protein that has been robustly linked to the pathogenesis of a number of neurodegenerative disorders, including amyotrophic lateral sclerosis and frontotemporal dementia. While mutations in the TARDBP gene that codes for the protein have been identified as causing disease in...

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Detalles Bibliográficos
Autores principales: Chen, Han-Jou, Mitchell, Jacqueline C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199531/
https://www.ncbi.nlm.nih.gov/pubmed/34199367
http://dx.doi.org/10.3390/ijms22116004

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