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Discovery of Novel Small-Molecule Inhibitors of PD-1/PD-L1 Interaction via Structural Simplification Strategy

Blockade of the programmed cell death 1 (PD-1)/programmed cell death-ligand 1 (PD-L1) interaction is currently the focus in the field of cancer immunotherapy, and so far, several monoclonal antibodies (mAbs) have achieved encouraging outcomes in cancer treatment. Despite this achievement, mAbs-based...

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Detalles Bibliográficos
Autores principales:	Zhang, Hongbo, Xia, Yu, Yu, Chunqiu, Du, Huijie, Liu, Jinchang, Li, Hui, Huang, Shihui, Zhu, Qihua, Xu, Yungen, Zou, Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199613/ https://www.ncbi.nlm.nih.gov/pubmed/34199417 http://dx.doi.org/10.3390/molecules26113347

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