Cargando…

Involvement of Neutrophils in Metastatic Evolution of Pancreatic Neuroendocrine Tumors

SIMPLE SUMMARY: The neutrophil-to-lymphocytes (NLR) reflects the systemic inflammation. Based on a cohort of 144 patients treated for localized or metastatic well-differentiated pancreatic neuroendocrine tumors (pNET), we identified the NLR ≥ 4 to be associated with worse overall survival. Using MCP...

Descripción completa

Detalles Bibliográficos
Autores principales:	Debien, Véronique, Davidson, Guillaume, Baltzinger, Philippe, Kurtz, Jean-Emmanuel, Séverac, François, Imperiale, Alessio, Pessaux, Patrick, Addeo, Pietro, Bachellier, Philippe, Su, Xiaoping, Davidson, Irwin, Chenard, Marie-Pierrette, Goichot, Bernard, Malouf, Gabriel G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199674/ https://www.ncbi.nlm.nih.gov/pubmed/34199561 http://dx.doi.org/10.3390/cancers13112771

Ejemplares similares

Simultaneous Resection of Pancreatic Neuroendocrine Tumors with Synchronous Liver Metastases: Safety and Oncological Efficacy
por: Addeo, Pietro, et al.
Publicado: (2022)

Metabolomics of Small Intestine Neuroendocrine Tumors and Related Hepatic Metastases
por: Imperiale, Alessio, et al.
Publicado: (2019)

Nuclear medicine imaging of gastro-entero-pancreatic neuroendocrine tumors. The key role of cellular differentiation and tumor grade: from theory to clinical practice
por: Rust, Edmond, et al.
Publicado: (2012)

Liver-Directed Therapy for Neuroendocrine Metastases: From Interventional Radiology to Nuclear Medicine Procedures
por: Cazzato, Roberto Luigi, et al.
Publicado: (2021)

Immune-Desert Tumor Microenvironment in Thoracic SMARCA4-Deficient Undifferentiated Tumors with Limited Efficacy of Immune Checkpoint Inhibitors
por: Gantzer, Justine, et al.
Publicado: (2022)

SMARCB1 regulates a TFCP2L1-MYC transcriptional switch promoting renal medullary carcinoma transformation and ferroptosis resistance
por: Vokshi, Bujamin H., et al.
Publicado: (2023)

A New Specific Succinate-Glutamate Metabolomic Hallmark in Sdhx-Related Paragangliomas
por: Imperiale, Alessio, et al.
Publicado: (2013)

Atypical hemolytic and uremic syndrome due to C3 mutation in pancreatic islet transplantation: a case report
por: Bahougne, Thibault, et al.
Publicado: (2020)

Sarcomatoid Dedifferentiation in Renal Cell Carcinoma: From Novel Molecular Insights to New Clinical Opportunities
por: Debien, Véronique, et al.
Publicado: (2019)

Neuroendocrine Tumors: Treatment and Management
por: Imperiale, Alessio
Publicado: (2022)

Laparoscopic treatment of biliary peritonitis following nonoperative management of blunt liver trauma
por: Marzano, Ettore, et al.
Publicado: (2010)

Metabolome Profiling by HRMAS NMR Spectroscopy of Pheochromocytomas and Paragangliomas Detects SDH Deficiency: Clinical and Pathophysiological Implications()()
por: Imperiale, Alessio, et al.
Publicado: (2015)

Malignant Rhabdoid Tumour of the Liver in the Young Adult: Report of First Two Cases
por: Marzano, Ettore, et al.
Publicado: (2009)

The LncRNA LENOX Interacts with RAP2C to Regulate Metabolism and Promote Resistance to MAPK Inhibition in Melanoma
por: Gambi, Giovanni, et al.
Publicado: (2022)

Spatiotemporal dynamics of calcium signals during neutrophil cluster formation
por: Khazen, Roxana, et al.
Publicado: (2022)

Prognostic value of the neutrophil/lymphocyte ratio in enteropancreatic neuroendocrine tumors
por: Grenader, Tal, et al.
Publicado: (2020)

Comprehensive integrative profiling of upper tract urothelial carcinomas
por: Su, Xiaoping, et al.
Publicado: (2021)

18F-FDG primary tumor uptake to improve N status prediction in cT1 non-metastatic non-small cell lung cancer: development and validation of a positron emission tomography model
por: Morland, David, et al.
Publicado: (2023)

Single cell transcriptomics reveal trans-differentiation of pancreatic beta cells following inactivation of the TFIID subunit Taf4
por: Kleiber, Thomas, et al.
Publicado: (2021)

TRF2 is recruited to the pre-initiation complex as a testis-specific subunit of TFIIA/ALF to promote haploid cell gene expression
por: Martianov, Igor, et al.
Publicado: (2016)

Postsurgical Presentation of Zollinger–Ellison Syndrome After Resection of Endometrioid Neuroendocrine Tumor
por: Almuhaidb, Aymen, et al.
Publicado: (2021)

Cutting-Edge Imaging of Cardiac Metastases from Neuroendocrine Tumors: Lesson from a Case Series
por: El Ghannudi, Soraya, et al.
Publicado: (2022)

Linking rapid erosion of the Mekong River delta to human activities
por: Anthony, Edward J., et al.
Publicado: (2015)

Silencing of genes by promoter hypermethylation shapes tumor microenvironment and resistance to immunotherapy in clear-cell renal cell carcinomas
por: Lu, Xiaofan, et al.
Publicado: (2023)

(18)F-FDOPA PET/CT Combined with MRI for Gross Tumor Volume Delineation in Patients with Skull Base Paraganglioma
por: Helali, Mehdi, et al.
Publicado: (2019)

Mixed neuroendocrine/Non-neuroendocrine neoplasm (MiNEN) of gastrointestinal lineage arising in an ovarian mature cystic teratoma
por: Dasaraju, Sandhyarani, et al.
Publicado: (2022)

Citrullination of pyruvate kinase M2 by PADI1 and PADI3 regulates glycolysis and cancer cell proliferation
por: Coassolo, Sébastien, et al.
Publicado: (2021)

TEAD transcription factors are required for normal primary myoblast differentiation in vitro and muscle regeneration in vivo
por: Joshi, Shilpy, et al.
Publicado: (2017)

HER2-Low Breast Cancer: Molecular Characteristics and Prognosis
por: Agostinetto, Elisa, et al.
Publicado: (2021)

Antibody–drug conjugates: the evolving field of targeted chemotherapy for breast cancer treatment
por: Nader-Marta, Guilherme, et al.
Publicado: (2023)

What Is the Quality of Life in Patients Treated with Levothyroxine for Hypothyroidism and How Are We Measuring It? A Critical, Narrative Review
por: Borson-Chazot, Françoise, et al.
Publicado: (2021)

Natural History and Treatment Strategies of Advanced PEComas: A Systematic Review
por: Bourgmayer, Agathe, et al.
Publicado: (2021)

Advanced Applications of Robotics in Digestive Surgery
por: Patriti, Alberto, et al.
Publicado: (2011)

Cancer subtypes classification using long non-coding RNA
por: Flippot, Ronan, et al.
Publicado: (2016)

Metabolomics approaches in pancreatic adenocarcinoma: tumor metabolism profiling predicts clinical outcome of patients
por: Battini, S., et al.
Publicado: (2017)

Quantitative and predictive model of kinetic regulation by E. coli TPP riboswitches
por: Guedich, Sondés, et al.
Publicado: (2016)

Neuroendocrine Disturbances in Huntington's Disease
por: Saleh, Nadine, et al.
Publicado: (2009)

Low density neutrophils are increased in patients with Behçet’s disease but do not explain differences in neutrophil function
por: Murad, Mariam, et al.
Publicado: (2022)

THE INTERACTION OF MYCOPLASMAS WITH MAMMALIAN CELLS : I. HELA CELLS, NEUTROPHILS, AND EOSINOPHILS
por: Zucker-Franklin, Dorothea, et al.
Publicado: (1966)

P482: ACCUFUSION: A HIGHLY SCALABLE SOFTWARE TOOL FOR DETECTING GENE FUSIONS BY RNA-SEQ IN LEUKEMIA
por: Su, Xiaoping, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_c0q5u3rpb4hc3rnma23mn9a2g6