Cargando…
The Association of Post-Concussion and Post-Traumatic Stress Disorder Symptoms with Health-Related Quality of Life, Health Care Use and Return-to-Work after Mild Traumatic Brain Injury
Patients with mild traumatic brain injury (mTBI) are at risk for post-concussion (PC) symptoms and post-traumatic stress disorder (PTSD). The co-occurrence of PC and PTSD symptoms after mTBI in relation to health-related quality of life (HRQoL), health care utilization, and return to work has not ye...
Autores principales: | , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199686/ https://www.ncbi.nlm.nih.gov/pubmed/34199591 http://dx.doi.org/10.3390/jcm10112473 |
_version_ | 1783707435330961408 |
---|---|
author | van der Vlegel, Marjolein Polinder, Suzanne Mikolic, Ana Kaplan, Rana von Steinbuechel, Nicole Plass, Anne Marie Zeldovich, Marina van Praag, Dominique Bockhop, Fabian Cunitz, Katrin Mueller, Isabelle Haagsma, Juanita A. |
author_facet | van der Vlegel, Marjolein Polinder, Suzanne Mikolic, Ana Kaplan, Rana von Steinbuechel, Nicole Plass, Anne Marie Zeldovich, Marina van Praag, Dominique Bockhop, Fabian Cunitz, Katrin Mueller, Isabelle Haagsma, Juanita A. |
author_sort | van der Vlegel, Marjolein |
collection | PubMed |
description | Patients with mild traumatic brain injury (mTBI) are at risk for post-concussion (PC) symptoms and post-traumatic stress disorder (PTSD). The co-occurrence of PC and PTSD symptoms after mTBI in relation to health-related quality of life (HRQoL), health care utilization, and return to work has not yet been investigated. PC and PTSD symptoms were measured six months post-TBI by respectively the Rivermead Post-Concussion Symptoms Questionnaire (RPQ) and the Post-Traumatic Stress Disorder Checklist for DSM-5 (PCL-5). Of the 1566 individuals after mTBI who met the inclusion criteria, 26.1% experienced PC symptoms (RPQ ≥16). Additionally, 9.8% experienced PTSD symptoms (PCL-5 ≥ 33), of which the vast majority (81%) also reported experiencing PC symptoms. Differences between patients with no/mild symptoms, with only PC, only PTSD, and both PC and PTSD symptoms in HRQoL, return to work, and rehabilitation were analyzed using logistic and linear regression analyses. Patients with PC and/or PTSD symptoms reported lower HRQoL, higher rates of rehabilitation, and lower return to work rates compared to patients with no/mild symptoms. Patients with both PC and PTSD symptoms reported significantly lower HRQoL (B = −2.73, CI = −4.65; −0.83, p < 0.001) compared to those with only PC symptoms, while there were no significant differences in their ongoing rehabilitation care (OR = 1.39, CI = 0.77–2.49, p = 0.272) and return to work rates (OR = 0.49, CI = 0.15–1.63, p = 0.246) at six months. These results underline the importance of the diagnosis and appropriate treatment of patients with mTBI, experiencing PC and/or PTSD symptoms. |
format | Online Article Text |
id | pubmed-8199686 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-81996862021-06-14 The Association of Post-Concussion and Post-Traumatic Stress Disorder Symptoms with Health-Related Quality of Life, Health Care Use and Return-to-Work after Mild Traumatic Brain Injury van der Vlegel, Marjolein Polinder, Suzanne Mikolic, Ana Kaplan, Rana von Steinbuechel, Nicole Plass, Anne Marie Zeldovich, Marina van Praag, Dominique Bockhop, Fabian Cunitz, Katrin Mueller, Isabelle Haagsma, Juanita A. J Clin Med Article Patients with mild traumatic brain injury (mTBI) are at risk for post-concussion (PC) symptoms and post-traumatic stress disorder (PTSD). The co-occurrence of PC and PTSD symptoms after mTBI in relation to health-related quality of life (HRQoL), health care utilization, and return to work has not yet been investigated. PC and PTSD symptoms were measured six months post-TBI by respectively the Rivermead Post-Concussion Symptoms Questionnaire (RPQ) and the Post-Traumatic Stress Disorder Checklist for DSM-5 (PCL-5). Of the 1566 individuals after mTBI who met the inclusion criteria, 26.1% experienced PC symptoms (RPQ ≥16). Additionally, 9.8% experienced PTSD symptoms (PCL-5 ≥ 33), of which the vast majority (81%) also reported experiencing PC symptoms. Differences between patients with no/mild symptoms, with only PC, only PTSD, and both PC and PTSD symptoms in HRQoL, return to work, and rehabilitation were analyzed using logistic and linear regression analyses. Patients with PC and/or PTSD symptoms reported lower HRQoL, higher rates of rehabilitation, and lower return to work rates compared to patients with no/mild symptoms. Patients with both PC and PTSD symptoms reported significantly lower HRQoL (B = −2.73, CI = −4.65; −0.83, p < 0.001) compared to those with only PC symptoms, while there were no significant differences in their ongoing rehabilitation care (OR = 1.39, CI = 0.77–2.49, p = 0.272) and return to work rates (OR = 0.49, CI = 0.15–1.63, p = 0.246) at six months. These results underline the importance of the diagnosis and appropriate treatment of patients with mTBI, experiencing PC and/or PTSD symptoms. MDPI 2021-06-02 /pmc/articles/PMC8199686/ /pubmed/34199591 http://dx.doi.org/10.3390/jcm10112473 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article van der Vlegel, Marjolein Polinder, Suzanne Mikolic, Ana Kaplan, Rana von Steinbuechel, Nicole Plass, Anne Marie Zeldovich, Marina van Praag, Dominique Bockhop, Fabian Cunitz, Katrin Mueller, Isabelle Haagsma, Juanita A. The Association of Post-Concussion and Post-Traumatic Stress Disorder Symptoms with Health-Related Quality of Life, Health Care Use and Return-to-Work after Mild Traumatic Brain Injury |
title | The Association of Post-Concussion and Post-Traumatic Stress Disorder Symptoms with Health-Related Quality of Life, Health Care Use and Return-to-Work after Mild Traumatic Brain Injury |
title_full | The Association of Post-Concussion and Post-Traumatic Stress Disorder Symptoms with Health-Related Quality of Life, Health Care Use and Return-to-Work after Mild Traumatic Brain Injury |
title_fullStr | The Association of Post-Concussion and Post-Traumatic Stress Disorder Symptoms with Health-Related Quality of Life, Health Care Use and Return-to-Work after Mild Traumatic Brain Injury |
title_full_unstemmed | The Association of Post-Concussion and Post-Traumatic Stress Disorder Symptoms with Health-Related Quality of Life, Health Care Use and Return-to-Work after Mild Traumatic Brain Injury |
title_short | The Association of Post-Concussion and Post-Traumatic Stress Disorder Symptoms with Health-Related Quality of Life, Health Care Use and Return-to-Work after Mild Traumatic Brain Injury |
title_sort | association of post-concussion and post-traumatic stress disorder symptoms with health-related quality of life, health care use and return-to-work after mild traumatic brain injury |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199686/ https://www.ncbi.nlm.nih.gov/pubmed/34199591 http://dx.doi.org/10.3390/jcm10112473 |
work_keys_str_mv | AT vandervlegelmarjolein theassociationofpostconcussionandposttraumaticstressdisordersymptomswithhealthrelatedqualityoflifehealthcareuseandreturntoworkaftermildtraumaticbraininjury AT polindersuzanne theassociationofpostconcussionandposttraumaticstressdisordersymptomswithhealthrelatedqualityoflifehealthcareuseandreturntoworkaftermildtraumaticbraininjury AT mikolicana theassociationofpostconcussionandposttraumaticstressdisordersymptomswithhealthrelatedqualityoflifehealthcareuseandreturntoworkaftermildtraumaticbraininjury AT kaplanrana theassociationofpostconcussionandposttraumaticstressdisordersymptomswithhealthrelatedqualityoflifehealthcareuseandreturntoworkaftermildtraumaticbraininjury AT vonsteinbuechelnicole theassociationofpostconcussionandposttraumaticstressdisordersymptomswithhealthrelatedqualityoflifehealthcareuseandreturntoworkaftermildtraumaticbraininjury AT plassannemarie theassociationofpostconcussionandposttraumaticstressdisordersymptomswithhealthrelatedqualityoflifehealthcareuseandreturntoworkaftermildtraumaticbraininjury AT zeldovichmarina theassociationofpostconcussionandposttraumaticstressdisordersymptomswithhealthrelatedqualityoflifehealthcareuseandreturntoworkaftermildtraumaticbraininjury AT vanpraagdominique theassociationofpostconcussionandposttraumaticstressdisordersymptomswithhealthrelatedqualityoflifehealthcareuseandreturntoworkaftermildtraumaticbraininjury AT bockhopfabian theassociationofpostconcussionandposttraumaticstressdisordersymptomswithhealthrelatedqualityoflifehealthcareuseandreturntoworkaftermildtraumaticbraininjury AT cunitzkatrin theassociationofpostconcussionandposttraumaticstressdisordersymptomswithhealthrelatedqualityoflifehealthcareuseandreturntoworkaftermildtraumaticbraininjury AT muellerisabelle theassociationofpostconcussionandposttraumaticstressdisordersymptomswithhealthrelatedqualityoflifehealthcareuseandreturntoworkaftermildtraumaticbraininjury AT haagsmajuanitaa theassociationofpostconcussionandposttraumaticstressdisordersymptomswithhealthrelatedqualityoflifehealthcareuseandreturntoworkaftermildtraumaticbraininjury AT theassociationofpostconcussionandposttraumaticstressdisordersymptomswithhealthrelatedqualityoflifehealthcareuseandreturntoworkaftermildtraumaticbraininjury AT vandervlegelmarjolein associationofpostconcussionandposttraumaticstressdisordersymptomswithhealthrelatedqualityoflifehealthcareuseandreturntoworkaftermildtraumaticbraininjury AT polindersuzanne associationofpostconcussionandposttraumaticstressdisordersymptomswithhealthrelatedqualityoflifehealthcareuseandreturntoworkaftermildtraumaticbraininjury AT mikolicana associationofpostconcussionandposttraumaticstressdisordersymptomswithhealthrelatedqualityoflifehealthcareuseandreturntoworkaftermildtraumaticbraininjury AT kaplanrana associationofpostconcussionandposttraumaticstressdisordersymptomswithhealthrelatedqualityoflifehealthcareuseandreturntoworkaftermildtraumaticbraininjury AT vonsteinbuechelnicole associationofpostconcussionandposttraumaticstressdisordersymptomswithhealthrelatedqualityoflifehealthcareuseandreturntoworkaftermildtraumaticbraininjury AT plassannemarie associationofpostconcussionandposttraumaticstressdisordersymptomswithhealthrelatedqualityoflifehealthcareuseandreturntoworkaftermildtraumaticbraininjury AT zeldovichmarina associationofpostconcussionandposttraumaticstressdisordersymptomswithhealthrelatedqualityoflifehealthcareuseandreturntoworkaftermildtraumaticbraininjury AT vanpraagdominique associationofpostconcussionandposttraumaticstressdisordersymptomswithhealthrelatedqualityoflifehealthcareuseandreturntoworkaftermildtraumaticbraininjury AT bockhopfabian associationofpostconcussionandposttraumaticstressdisordersymptomswithhealthrelatedqualityoflifehealthcareuseandreturntoworkaftermildtraumaticbraininjury AT cunitzkatrin associationofpostconcussionandposttraumaticstressdisordersymptomswithhealthrelatedqualityoflifehealthcareuseandreturntoworkaftermildtraumaticbraininjury AT muellerisabelle associationofpostconcussionandposttraumaticstressdisordersymptomswithhealthrelatedqualityoflifehealthcareuseandreturntoworkaftermildtraumaticbraininjury AT haagsmajuanitaa associationofpostconcussionandposttraumaticstressdisordersymptomswithhealthrelatedqualityoflifehealthcareuseandreturntoworkaftermildtraumaticbraininjury AT associationofpostconcussionandposttraumaticstressdisordersymptomswithhealthrelatedqualityoflifehealthcareuseandreturntoworkaftermildtraumaticbraininjury |