Spectroscopic and In Silico Studies on the Interaction of Substituted Pyrazolo[1,2-a]benzo[1,2,3,4]tetrazine-3-one Derivatives with c-Myc G4-DNA

Herein we describe a combined experimental and in silico study of the interaction of a series of pyrazolo[1,2-a]benzo[1,2,3,4]tetrazin-3-one derivatives (PBTs) with parallel G-quadruplex (GQ) DNA aimed at correlating their previously reported anticancer activities and the stabilizing effects observe...

Descripción completa

Detalles Bibliográficos
Autores principales: Mulliri, Simone, Laaksonen, Aatto, Spanu, Pietro, Farris, Riccardo, Farci, Matteo, Mingoia, Francesco, Roviello, Giovanni N., Mocci, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199725/
https://www.ncbi.nlm.nih.gov/pubmed/34199659
http://dx.doi.org/10.3390/ijms22116028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199725/
https://www.ncbi.nlm.nih.gov/pubmed/34199659
http://dx.doi.org/10.3390/ijms22116028

Ejemplares similares