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Red Blood Cell Transfusion in the Emergency Department: An Observational Cross-Sectional Multicenter Study
Background: We aimed to describe red blood cell (RBC) transfusions in the emergency department (ED) with a particular focus on the hemoglobin (Hb) level thresholds that are used in this setting. Methods: This was a cross-sectional study of 12 EDs including all adult patients that received RBC transf...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199757/ https://www.ncbi.nlm.nih.gov/pubmed/34199655 http://dx.doi.org/10.3390/jcm10112475 |
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author | Peyrony, Olivier Gamelon, Danaé Brune, Romain Chauvin, Anthony Ghazali, Daniel Aiham Yordanov, Youri Arsicaud, Aude Gilleron, Pauline Curac, Sonja Richard, Marie-Caroline Feral-Pierssens, Anne-Laure Villoing, Barbara Beaune, Sébastien Goulet, Hélène Fontaine, Jean-Paul François, Anne Pirenne, France |
author_facet | Peyrony, Olivier Gamelon, Danaé Brune, Romain Chauvin, Anthony Ghazali, Daniel Aiham Yordanov, Youri Arsicaud, Aude Gilleron, Pauline Curac, Sonja Richard, Marie-Caroline Feral-Pierssens, Anne-Laure Villoing, Barbara Beaune, Sébastien Goulet, Hélène Fontaine, Jean-Paul François, Anne Pirenne, France |
author_sort | Peyrony, Olivier |
collection | PubMed |
description | Background: We aimed to describe red blood cell (RBC) transfusions in the emergency department (ED) with a particular focus on the hemoglobin (Hb) level thresholds that are used in this setting. Methods: This was a cross-sectional study of 12 EDs including all adult patients that received RBC transfusion in January and February 2018. Descriptive statistics were reported. Logistic regression was performed to assess variables that were independently associated with a pre-transfusion Hb level ≥ 8 g/dL. Results: During the study period, 529 patients received RBC transfusion. The median age was 74 (59–85) years. The patients had a history of cancer or hematological disease in 185 (35.2%) cases. Acute bleeding was observed in the ED for 242 (44.7%) patients, among which 145 (59.9%) were gastrointestinal. Anemia was chronic in 191 (40.2%) cases, mostly due to vitamin or iron deficiency or to malignancy with transfusion support. Pre-transfusion Hb level was 6.9 (6.0–7.8) g/dL. The transfusion motive was not notified in the medical chart in 206 (38.9%) cases. In the multivariable logistic regression, variables that were associated with a higher pre-transfusion Hb level (≥8 g/dL) were a history of coronary artery disease (OR: 2.09; 95% CI: 1.29–3.41), the presence of acute bleeding (OR: 2.44; 95% CI: 1.53–3.94), and older age (OR: 1.02/year; 95% CI: 1.01–1.04). Conclusion: RBC transfusion in the ED was an everyday concern and involved patients with heterogeneous medical situations and severity. Pre-transfusion Hb level was rather restrictive. Almost half of transfusions were provided because of acute bleeding which was associated with a higher Hb threshold. |
format | Online Article Text |
id | pubmed-8199757 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-81997572021-06-14 Red Blood Cell Transfusion in the Emergency Department: An Observational Cross-Sectional Multicenter Study Peyrony, Olivier Gamelon, Danaé Brune, Romain Chauvin, Anthony Ghazali, Daniel Aiham Yordanov, Youri Arsicaud, Aude Gilleron, Pauline Curac, Sonja Richard, Marie-Caroline Feral-Pierssens, Anne-Laure Villoing, Barbara Beaune, Sébastien Goulet, Hélène Fontaine, Jean-Paul François, Anne Pirenne, France J Clin Med Article Background: We aimed to describe red blood cell (RBC) transfusions in the emergency department (ED) with a particular focus on the hemoglobin (Hb) level thresholds that are used in this setting. Methods: This was a cross-sectional study of 12 EDs including all adult patients that received RBC transfusion in January and February 2018. Descriptive statistics were reported. Logistic regression was performed to assess variables that were independently associated with a pre-transfusion Hb level ≥ 8 g/dL. Results: During the study period, 529 patients received RBC transfusion. The median age was 74 (59–85) years. The patients had a history of cancer or hematological disease in 185 (35.2%) cases. Acute bleeding was observed in the ED for 242 (44.7%) patients, among which 145 (59.9%) were gastrointestinal. Anemia was chronic in 191 (40.2%) cases, mostly due to vitamin or iron deficiency or to malignancy with transfusion support. Pre-transfusion Hb level was 6.9 (6.0–7.8) g/dL. The transfusion motive was not notified in the medical chart in 206 (38.9%) cases. In the multivariable logistic regression, variables that were associated with a higher pre-transfusion Hb level (≥8 g/dL) were a history of coronary artery disease (OR: 2.09; 95% CI: 1.29–3.41), the presence of acute bleeding (OR: 2.44; 95% CI: 1.53–3.94), and older age (OR: 1.02/year; 95% CI: 1.01–1.04). Conclusion: RBC transfusion in the ED was an everyday concern and involved patients with heterogeneous medical situations and severity. Pre-transfusion Hb level was rather restrictive. Almost half of transfusions were provided because of acute bleeding which was associated with a higher Hb threshold. MDPI 2021-06-02 /pmc/articles/PMC8199757/ /pubmed/34199655 http://dx.doi.org/10.3390/jcm10112475 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Peyrony, Olivier Gamelon, Danaé Brune, Romain Chauvin, Anthony Ghazali, Daniel Aiham Yordanov, Youri Arsicaud, Aude Gilleron, Pauline Curac, Sonja Richard, Marie-Caroline Feral-Pierssens, Anne-Laure Villoing, Barbara Beaune, Sébastien Goulet, Hélène Fontaine, Jean-Paul François, Anne Pirenne, France Red Blood Cell Transfusion in the Emergency Department: An Observational Cross-Sectional Multicenter Study |
title | Red Blood Cell Transfusion in the Emergency Department: An Observational Cross-Sectional Multicenter Study |
title_full | Red Blood Cell Transfusion in the Emergency Department: An Observational Cross-Sectional Multicenter Study |
title_fullStr | Red Blood Cell Transfusion in the Emergency Department: An Observational Cross-Sectional Multicenter Study |
title_full_unstemmed | Red Blood Cell Transfusion in the Emergency Department: An Observational Cross-Sectional Multicenter Study |
title_short | Red Blood Cell Transfusion in the Emergency Department: An Observational Cross-Sectional Multicenter Study |
title_sort | red blood cell transfusion in the emergency department: an observational cross-sectional multicenter study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199757/ https://www.ncbi.nlm.nih.gov/pubmed/34199655 http://dx.doi.org/10.3390/jcm10112475 |
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