Cargando…

Venom-Derived Neurotoxins Targeting Nicotinic Acetylcholine Receptors

Acetylcholine was the first neurotransmitter described. The receptors targeted by acetylcholine are found within organisms spanning different phyla and position themselves as very attractive targets for predation, as well as for defense. Venoms of snakes within the Elapidae family, as well as those...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bekbossynova, Ayaulym, Zharylgap, Albina, Filchakova, Olena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199771/ https://www.ncbi.nlm.nih.gov/pubmed/34204855 http://dx.doi.org/10.3390/molecules26113373

Ejemplares similares

RC-4BC cells express nicotinic and muscarinic acetylcholine receptors
por: Zhubanova, Gulsamal, et al.
Publicado: (2022)

Inhibition of the Nicotinic Acetylcholine Receptors by Cobra Venom α-Neurotoxins: Is There a Perspective in Lung Cancer Treatment?
por: Alama, Angela, et al.
Publicado: (2011)

Functional Expression of Human α9* Nicotinic Acetylcholine Receptors in X. laevis Oocytes Is Dependent on the α9 Subunit 5′ UTR
por: Filchakova, Olena, et al.
Publicado: (2013)

Novel Three-Finger Neurotoxins from Naja melanoleuca Cobra Venom Interact with GABA(A) and Nicotinic Acetylcholine Receptors
por: Son, Lina, et al.
Publicado: (2021)

An in vitro assay to investigate venom neurotoxin activity on muscle-type nicotinic acetylcholine receptor activation and for the discovery of toxin-inhibitory molecules
por: Patel, Rohit N., et al.
Publicado: (2023)

Conotoxins Targeting Nicotinic Acetylcholine Receptors: An Overview
por: Lebbe, Eline K. M., et al.
Publicado: (2014)

Nicotinic acetylcholine receptors and cancer
por: DANG, NINGNING, et al.
Publicado: (2016)

The molecular mechanism of snake short-chain α-neurotoxin binding to muscle-type nicotinic acetylcholine receptors
por: Nys, Mieke, et al.
Publicado: (2022)

Nicotinic Acetylcholine Receptors in the Respiratory Tract
por: Hollenhorst, Monika I., et al.
Publicado: (2021)

Structural model of nicotinic acetylcholine receptor isotypes bound to acetylcholine and nicotine
por: Schapira, Matthieu, et al.
Publicado: (2002)

The Oncogenic Functions of Nicotinic Acetylcholine Receptors
por: Zhao, Yue
Publicado: (2016)

The Nicotinic Acetylcholine Receptor as a Target for Antidepressant Drug Development
por: Philip, Noah S., et al.
Publicado: (2012)

What Are the Neurotoxins in Hemotoxic Snake Venoms?
por: Osipov, Alexey, et al.
Publicado: (2023)

Pancreatic and snake venom presynaptically active phospholipases A(2) inhibit nicotinic acetylcholine receptors
por: Vulfius, Catherine A., et al.
Publicado: (2017)

Alpha7 Nicotinic Acetylcholine Receptor Is a Target in Pharmacology and Toxicology
por: Pohanka, Miroslav
Publicado: (2012)

Nicotinic Acetylcholine Receptors and Microglia as Therapeutic and Imaging Targets in Alzheimer’s Disease
por: Takata, Kazuyuki, et al.
Publicado: (2022)

Discovery of the First Neurotransmitter Receptor: The Acetylcholine Nicotinic Receptor
por: Changeux, Jean-Pierre
Publicado: (2020)

From Smoking to Cancers: Novel Targets to Neuronal Nicotinic Acetylcholine Receptors
por: Lee, Chia-Hwa, et al.
Publicado: (2011)

The submembrane machinery for nicotinic acetylcholine receptor clustering
Publicado: (1991)

Pathogenesis of Abdominal Aortic Aneurysms: Role of Nicotine and Nicotinic Acetylcholine Receptors
por: Li, Zong-Zhuang, et al.
Publicado: (2012)

Azemiopsin from Azemiops feae Viper Venom, a Novel Polypeptide Ligand of Nicotinic Acetylcholine Receptor
por: Utkin, Yuri N., et al.
Publicado: (2012)

The Target Selects the Toxin: Specific Amino Acids in Snake-Prey Nicotinic Acetylcholine Receptors That Are Selectively Bound by King Cobra Venoms
por: Chandrasekara, Uthpala, et al.
Publicado: (2022)

Endogenous neurotoxin-like protein Ly6H inhibits alpha7 nicotinic acetylcholine receptor currents at the plasma membrane
por: Moriwaki, Yasuhiro, et al.
Publicado: (2020)

The Metabolic Stability of the Nicotinic Acetylcholine Receptor at the Neuromuscular Junction
por: Martinez-Pena y Valenzuela, Isabel, et al.
Publicado: (2021)

Nicotinic acetylcholine receptors modulate osteoclastogenesis
por: Mandl, Peter, et al.
Publicado: (2016)

Neuronal and Extraneuronal Nicotinic Acetylcholine Receptors
por: Zoli, Michele, et al.
Publicado: (2018)

Evolution of vertebrate nicotinic acetylcholine receptors
por: Pedersen, Julia E., et al.
Publicado: (2019)

Nicotinic Acetylcholine Receptor Signaling in Tumor Growth and Metastasis
por: Singh, Sandeep, et al.
Publicado: (2011)

Targeting α7 nicotinic acetylcholine receptors for chronic pain
por: Zhou, Ya-Qun, et al.
Publicado: (2022)

Inhibition of Nicotinic Acetylcholine Receptors, a Novel Facet in the Pleiotropic Activities of Snake Venom Phospholipases A(2)
por: Vulfius, Catherine A., et al.
Publicado: (2014)

Assessing the Binding of Venoms from Aquatic Elapids to the Nicotinic Acetylcholine Receptor Orthosteric Site of Different Prey Models
por: Harris, Richard J., et al.
Publicado: (2020)

Lynx Prototoxins: Roles of Endogenous Mammalian Neurotoxin-Like Proteins in Modulating Nicotinic Acetylcholine Receptor Function to Influence Complex Biological Processes
por: Miwa, Julie M., et al.
Publicado: (2019)

Acetylcholine receptors in the retinas of the α7 nicotinic acetylcholine receptor knockout mouse
por: Smith, Marci L., et al.
Publicado: (2014)

The Impact of Electronic Nicotine Delivery System (ENDS) Flavors on Nicotinic Acetylcholine Receptors and Nicotine Addiction-Related Behaviors
por: Cooper, Skylar Y., et al.
Publicado: (2020)

Neuronal Nicotinic Acetylcholine Receptor Modulators from Cone Snails
por: Abraham, Nikita, et al.
Publicado: (2018)

Acetylcholinesterase and Nicotinic Acetylcholine Receptors in Schistosomes and Other Parasitic Helminths
por: You, Hong, et al.
Publicado: (2017)

Recent Advances in the Discovery of Nicotinic Acetylcholine Receptor Allosteric Modulators
por: Manetti, Dina, et al.
Publicado: (2023)

Nicotinic acetylcholine receptors regulate clustering, fusion and acidification of the rat brain synaptic vesicles
por: Trikash, Irene, et al.
Publicado: (2020)

Different Effects of Nicotine and N-Stearoyl-ethanolamine on Episodic Memory and Brain Mitochondria of α7 Nicotinic Acetylcholine Receptor Knockout Mice
por: Lykhmus, Olena, et al.
Publicado: (2020)

Activities of nicotinic acetylcholine receptors modulate neurotransmission and synaptic architecture
por: Oda, Akira, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_j7uujpl15k2h1e36q3im45c80d