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(V600E)BRAF Inhibition Induces Cytoprotective Autophagy through AMPK in Thyroid Cancer Cells

The dysregulation of autophagy is important in the development of many cancers, including thyroid cancer, where (V600E)BRAF is a main oncogene. Here, we analyse the effect of (V600E)BRAF inhibition on autophagy, the mechanisms involved in this regulation and the role of autophagy in cell survival of...

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Detalles Bibliográficos
Autores principales: Jiménez-Mora, Eva, Gallego, Beatriz, Díaz-Gago, Sergio, Lasa, Marina, Baquero, Pablo, Chiloeches, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199856/
https://www.ncbi.nlm.nih.gov/pubmed/34204950
http://dx.doi.org/10.3390/ijms22116033