Role and Perspective of Molecular Simulation-Based Investigation of RNA–Ligand Interaction: From Small Molecules and Peptides to Photoswitchable RNA Binding

Aberrant RNA–protein complexes are formed in a variety of diseases. Identifying the ligands that interfere with their formation is a valuable therapeutic strategy. Molecular simulation, validated against experimental data, has recently emerged as a powerful tool to predict both the pose and energeti...

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Detalles Bibliográficos
Autores principales: Berdnikova, Daria V., Carloni, Paolo, Krauß, Sybille, Rossetti, Giulia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199858/
https://www.ncbi.nlm.nih.gov/pubmed/34205049
http://dx.doi.org/10.3390/molecules26113384

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199858/
https://www.ncbi.nlm.nih.gov/pubmed/34205049
http://dx.doi.org/10.3390/molecules26113384

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