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Sodium Glucose Co-Transporter 2 Inhibitors Ameliorate Endothelium Barrier Dysfunction Induced by Cyclic Stretch through Inhibition of Reactive Oxygen Species

SGLT-2i’s exert direct anti-inflammatory and anti-oxidative effects on resting endothelial cells. However, endothelial cells are constantly exposed to mechanical forces such as cyclic stretch. Enhanced stretch increases the production of reactive oxygen species (ROS) and thereby impairs endothelial...

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Detalles Bibliográficos
Autores principales:	Li, Xiaoling, Römer, Gregor, Kerindongo, Raphaela P., Hermanides, Jeroen, Albrecht, Martin, Hollmann, Markus W., Zuurbier, Coert J., Preckel, Benedikt, Weber, Nina C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199893/ https://www.ncbi.nlm.nih.gov/pubmed/34205045 http://dx.doi.org/10.3390/ijms22116044

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