Cargando…
A New Chalcone Derivative with Promising Antiproliferative and Anti-Invasion Activities in Glioblastoma Cells
Glioblastoma (GBM) is the most common and most deadly primary malignant brain tumor. Current therapies are not effective, the average survival of GBM patients after diagnosis being limited to few months. Therefore, the discovery of new treatments for this highly aggressive brain cancer is urgently n...
Autores principales: | Mendanha, Daniel, Vieira de Castro, Joana, Moreira, Joana, Costa, Bruno M., Cidade, Honorina, Pinto, Madalena, Ferreira, Helena, Neves, Nuno M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199914/ https://www.ncbi.nlm.nih.gov/pubmed/34205043 http://dx.doi.org/10.3390/molecules26113383 |
Ejemplares similares
-
Chalcones as Promising Antitumor Agents by Targeting the p53 Pathway: An Overview and New Insights in Drug-Likeness
por: Moreira, Joana, et al.
Publicado: (2021) -
Structure–Activity Relationship Studies of Chalcones and Diarylpentanoids with Antitumor Activity: Potency and Selectivity Optimization
por: Moreira, Joana, et al.
Publicado: (2023) -
New Chalcone–Triazole Hybrids with Promising Antimicrobial Activity in Multidrug Resistance Strains
por: Pereira, Daniela, et al.
Publicado: (2022) -
Discovery of a New Chalcone-Trimethoxycinnamide Hybrid with Antimitotic Effect: Design, Synthesis, and Structure—Activity Relationship Studies
por: Moreira, Joana, et al.
Publicado: (2023) -
Prenylated Chalcone 2 Acts as an Antimitotic Agent and Enhances the Chemosensitivity of Tumor Cells to Paclitaxel
por: Fonseca, Joana, et al.
Publicado: (2016)