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3D Multicellular Stem-Like Human Breast Tumor Spheroids Enhance Tumorigenicity of Orthotopic Xenografts in Athymic Nude Rat Model

SIMPLE SUMMARY: Breast cancer presents a unique clinical problem because of the variety of cellular subtypes present, including cancer stem cells (CSCs). Breast CSCs can induce the formation of new blood vessels at the site of tumor growth and a develop metastatic phenotype by enhancing a stromal ce...

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Detalles Bibliográficos
Autores principales: Mokhtari, Reza Bayat, Qorri, Bessi, Sambi, Manpreet, Baluch, Narges, Kumar, Sushil, Das, Bikul, Szewczuk, Myron R., Yeger, Herman, Cheng, Hai-Ling Margaret
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199968/
https://www.ncbi.nlm.nih.gov/pubmed/34205080
http://dx.doi.org/10.3390/cancers13112784