Cargando…

Exploring the Physiological Role of Transthyretin in Glucose Metabolism in the Liver

Transthyretin (TTR), a 55 kDa evolutionarily conserved protein, presents altered levels in several conditions, including malnutrition, inflammation, diabetes, and Alzheimer’s Disease. It has been shown that TTR is involved in several functions, such as insulin release from pancreatic β-cells, recove...

Descripción completa

Detalles Bibliográficos
Autores principales:	Alemi, Mobina, Oliveira, Ângela, Tavares, Sofia C., Vieira, José Ricardo, Alves, Marco G., Oliveira, Pedro F., Cardoso, Isabel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8200108/ https://www.ncbi.nlm.nih.gov/pubmed/34199897 http://dx.doi.org/10.3390/ijms22116073

Ejemplares similares

Transthyretin participates in beta-amyloid transport from the brain to the liver- involvement of the low-density lipoprotein receptor-related protein 1?
por: Alemi, Mobina, et al.
Publicado: (2016)

Radiochemical examination of transthyretin (TTR) brain penetration assisted by iododiflunisal, a TTR tetramer stabilizer and a new candidate drug for AD
por: Rios, Xabier, et al.
Publicado: (2019)

Repurposing Benzbromarone for Familial Amyloid Polyneuropathy: A New Transthyretin Tetramer Stabilizer
por: Cotrina, Ellen Y., et al.
Publicado: (2020)

Neuroprotection in early stages of Alzheimer’s disease is promoted by transthyretin angiogenic properties
por: Gião, Tiago, et al.
Publicado: (2021)

The Importance of a Gatekeeper Residue on the Aggregation of Transthyretin: IMPLICATIONS FOR TRANSTHYRETIN-RELATED AMYLOIDOSES
por: Sant'Anna, Ricardo, et al.
Publicado: (2014)

Extracellular Vesicles Contribute to the Metabolism of Transthyretin Amyloid in Hereditary Transthyretin Amyloidosis
por: Yamaguchi, Hiroki, et al.
Publicado: (2022)

A Metabolic Signature of Hereditary Transthyretin Amyloidosis: A Pilot Study
por: Luigetti, Marco, et al.
Publicado: (2022)

Transthyretin Stabilizers and Seeding Inhibitors as Therapies for Amyloid Transthyretin Cardiomyopathy
por: Morfino, Paolo, et al.
Publicado: (2023)

Liver‐directed drugs for transthyretin‐mediated amyloidosis
por: Brannagan, Thomas H., et al.
Publicado: (2022)

Diabetes, insulin-mediated glucose metabolism and Sertoli/blood-testis barrier function
por: Alves, Marco G., et al.
Publicado: (2013)

High-intensity infrasound effects on glucose metabolism in rats
por: Pereira, Gonçalo Martins, et al.
Publicado: (2021)

EGCG-Mediated Protection of Transthyretin Amyloidosis by Stabilizing Transthyretin Tetramers and Disrupting Transthyretin Aggregates
por: Zou, Huizhen, et al.
Publicado: (2023)

Transthyretin expression in the postischemic brain
por: Talhada, Daniela, et al.
Publicado: (2019)

Role of Glutamatergic Projections from Lateral Habenula to Ventral Tegmental Area in Inflammatory Pain-Related Spatial Working Memory Deficits
por: Alemi, Mobina, et al.
Publicado: (2023)

Dynamics of Lateral Habenula–Ventral Tegmental Area Microcircuit on Pain-Related Cognitive Dysfunctions
por: Pereira, Ana Raquel, et al.
Publicado: (2023)

Treatment of acquired transthyretin amyloidosis in domino liver transplantation
por: Tsamis, Konstantinos I., et al.
Publicado: (2022)

Hereditary transthyretin amyloidosis overview
por: Manganelli, Fiore, et al.
Publicado: (2020)

Temporal Trends of Wild-Type Transthyretin Amyloid Cardiomyopathy in the Transthyretin Amyloidosis Outcomes Survey
por: Nativi-Nicolau, Jose, et al.
Publicado: (2021)

Calcium Binds to Transthyretin with Low Affinity
por: Cantarutti, Cristina, et al.
Publicado: (2022)

Correction: Transthyretin expression in the postischemic brain
por: Talhada, Daniela, et al.
Publicado: (2020)

Stability of the Transthyretin Molecule as a Key Factor in the Interaction with A-Beta Peptide - Relevance in Alzheimer's Disease
por: Ribeiro, Carlos A., et al.
Publicado: (2012)

Evolving landscape in the management of transthyretin amyloidosis
por: Hawkins, Philip N., et al.
Publicado: (2015)

Frequency of hereditary transthyretin amyloidosis among elderly patients with transthyretin cardiomyopathy
por: Maestro‐Benedicto, Alba, et al.
Publicado: (2022)

Sex Differences in Wild-Type Transthyretin Amyloidosis: An Analysis from the Transthyretin Amyloidosis Outcomes Survey (THAOS)
por: Campbell, Courtney M., et al.
Publicado: (2022)

Delivery of an anti‐transthyretin Nanobody to the brain through intranasal administration reveals transthyretin expression and secretion by motor neurons
por: Gomes, João R., et al.
Publicado: (2018)

Transthyretin cardiac amyloidosis
por: Tomoaia, Raluca, et al.
Publicado: (2021)

Transthyretin cardiac amyloidosis
por: Porcari, Aldostefano, et al.
Publicado: (2022)

Epidemiology of transthyretin familial amyloid polyneuropathy in Portugal
por: Inês, Mónica, et al.
Publicado: (2015)

Transthyretin and the brain re-visited: Is neuronal synthesis of transthyretin protective in Alzheimer's disease?
por: Li, Xinyi, et al.
Publicado: (2011)

Hereditary transthyretin amyloidosis: a case report
por: Lee, Angela, et al.
Publicado: (2022)

Transthyretin interacts with actin regulators in a Drosophila model of familial amyloid polyneuropathy
por: I. Oliveira da Silva, Marina, et al.
Publicado: (2020)

Quantification of Quaternary Structure Stability in Aggregation-Prone Proteins under Physiological Conditions: The Transthyretin Case
por: Robinson, Lei Z., et al.
Publicado: (2014)

Synergy of combined Doxycycline/TUDCA treatment in lowering Transthyretin deposition and associated biomarkers: studies in FAP mouse models
por: Cardoso, Isabel, et al.
Publicado: (2010)

Undiscovered Roles for Transthyretin: From a Transporter Protein to a New Therapeutic Target for Alzheimer’s Disease
por: Gião, Tiago, et al.
Publicado: (2020)

Transthyretin Antisense Oligonucleotides Lower Circulating RBP4 Levels and Improve Insulin Sensitivity in Obese Mice
por: Zemany, Laura, et al.
Publicado: (2015)

Exploring the Applicability of Physiological Monitoring to Manage Physical Fatigue in Firefighters
por: Bustos, Denisse, et al.
Publicado: (2023)

Liver glucose metabolism in humans
por: Adeva-Andany, María M., et al.
Publicado: (2016)

Exploring the metabolic and physiological roles of HQT in S. lycopersicum by gene editing
por: D’Orso, Fabio, et al.
Publicado: (2023)

Interleukin-1 signaling pathway as a therapeutic target in transthyretin amyloidosis
por: Gonçalves, Nádia Pereira, et al.
Publicado: (2014)

Effect of Tafamidis on Serum Transthyretin Levels in Non-Trial Patients With Transthyretin Amyloid Cardiomyopathy
por: Falk, Rodney H., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_amsek607l8s5nq3au88ugce2a2