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Nrf2/Keap1-Pathway Activation and Reduced Susceptibility to Chemotherapy Treatment by Acidification in Esophageal Adenocarcinoma Cells

SIMPLE SUMMARY: Inflammation caused by acidic reflux contributes to disease progression in Barrett’s esophagus. Little is known, whether esophageal cancer cells are influenced by acidic reflux and whether reflux influences cancer cell physiology, targeting the Nrf2/Kepa1- and the NFκB-pathway. The u...

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Detalles Bibliográficos
Autores principales:	Storz, Lucie, Walther, Philipp, Chemnitzer, Olga, Lyros, Orestis, Niebisch, Stefan, Mehdorn, Matthias, Jansen-Winkeln, Boris, Moulla, Yusef, Büch, Thomas, Gockel, Ines, Thieme, René
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8200109/ https://www.ncbi.nlm.nih.gov/pubmed/34199909 http://dx.doi.org/10.3390/cancers13112806

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