Pharmacological Inhibition of CBP/p300 Blocks Estrogen Receptor Alpha (ERα) Function through Suppressing Enhancer H3K27 Acetylation in Luminal Breast Cancer

SIMPLE SUMMARY: Breast cancer is the most common cancer in women, affecting 1 in 20 women globally. Breast cancer is divided into four subtypes: luminal A, luminal B, HER2-enriched, and basal-like. Estrogen receptor-positive breast cancer accounts for nearly 80% of all breast cancer cases and most b...

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Detalles Bibliográficos
Autores principales: Waddell, Aaron, Mahmud, Iqbal, Ding, Haocheng, Huo, Zhiguang, Liao, Daiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8200112/
https://www.ncbi.nlm.nih.gov/pubmed/34199844
http://dx.doi.org/10.3390/cancers13112799

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